Lamotrigine and Rituxan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Rituxan (rituximab). Common drug interactions include dysphagia among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Rituxan. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.



On Jul, 09, 2026

61 people who take Lamotrigine and Rituxan together, and have interactions are studied.

Lamotrigine and Rituxan drug interactions.

What are the common drug interactions of Lamotrigine and Rituxan, by gender? *:

female:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Blood pressure decreased
  4. Diabetes mellitus inadequate control
  5. Drug dependence
  6. Influenza
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Abdominal discomfort
  9. Insomnia (sleeplessness)
  10. Pneumonia

male:

  1. Hypotension (abnormally low blood pressure)
  2. Pain
  3. Blood iron increased
  4. Blood pressure increased
  5. Chills (felling of cold)
  6. Communication disorder (speech and language disorder)
  7. Constipation
  8. Cough
  9. Diarrhoea
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the common drug interactions of Lamotrigine and Rituxan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal discomfort
  2. Dehydration (dryness resulting from the removal of water)
  3. Diarrhoea
  4. Drug ineffective
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Headache (pain in head)
  7. Hypotension (abnormally low blood pressure)
  8. Nausea (feeling of having an urge to vomit)
  9. Neuralgia (pain in one or more nerves)
  10. Oral pruritus (itching in mouth)

40-49:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Delirium (wild excitement)
  3. Emotional disorder
  4. Hypersensitivity
  5. Influenza like illness
  6. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  7. Acute respiratory failure
  8. Chylothorax (collection of lymph fluid around the lung)
  9. Dizziness postural
  10. Fall

50-59:

  1. Oxygen saturation decreased
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Headache (pain in head)
  4. Weight decreased
  5. Blood albumin increased
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Cushing's syndrome (obesity, a rounded face, increased fat)
  8. Inflammation
  9. Insomnia (sleeplessness)
  10. Lymph node pain

60+:

  1. Peripheral swelling
  2. Hypotension (abnormally low blood pressure)
  3. Chills (felling of cold)
  4. Communication disorder (speech and language disorder)
  5. Cough
  6. Diarrhoea
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Dyspnoea (difficult or laboured respiration)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Pain: 10 people, 16.39%
  2. Diabetes: 9 people, 14.75%
  3. Inflammation: 7 people, 11.48%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 8.20%
  5. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 8.20%
  6. Depression: 5 people, 8.20%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 8.20%
  8. Stress And Anxiety: 4 people, 6.56%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.56%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamotrigine and Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamotrigine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamotrigine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rituxan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine and rituximab (the active ingredients of Lamotrigine and Rituxan, respectively), and Lamotrigine and Rituxan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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