Lamotrigine and Symmetrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Symmetrel (amantadine hydrochloride). Common drug interactions include seizure among females and pneumonia aspiration among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Symmetrel. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Symmetrel?

Symmetrel has active ingredients of amantadine hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,398 Symmetrel users. Check the latest studies of Symmetrel.

On Jun, 11, 2026

11 people who take Lamotrigine and Symmetrel together, and have interactions are studied.

Lamotrigine and Symmetrel drug interactions.

What are the common drug interactions of Lamotrigine and Symmetrel, by gender? *:

female:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dizziness
Erythema (redness of the skin)
Kidney infection
Radiation injury (injuries are caused by radiation)
Rash
Rehabilitation therapy
Speech disorder

male:

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the common drug interactions of Lamotrigine and Symmetrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

30-39:

n/a

40-49:

General symptom
Influenza like illness
Memory impairment
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Speech disorder

50-59:

n/a

60+:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Anaphylactic reaction (serious allergic reaction)
Kidney infection
Rash
Rehabilitation therapy
Tremor (trembling or shaking movements in one or more parts of your body)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Weight decreased
Dementia (madness)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 54.55%
Constipation: 3 people, 27.27%
Stress And Anxiety: 2 people, 18.18%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 18.18%
Heart Disease: 2 people, 18.18%
Headache (pain in head): 2 people, 18.18%
Fatigue (feeling of tiredness): 2 people, 18.18%
Depression: 2 people, 18.18%
Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 9.09%
Seizure Cluster (small group of seizure): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Lamotrigine and Symmetrel?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously