Lamotrigine and Xopenex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamotrigine (lamotrigine) and Xopenex (levalbuterol hydrochloride). Common drug interactions include myasthenia gravis among females and endotracheal intubation complication among males.

The phase IV clinical study analyzes what interactions people have when they take Lamotrigine and Xopenex. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.

On Jul, 25, 2026

80 people who take Lamotrigine and Xopenex together, and have interactions are studied.

Lamotrigine and Xopenex drug interactions.

What are the common drug interactions of Lamotrigine and Xopenex, by gender? *:

female:

Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Renal cyst (kidney cyst)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Spinal meningeal cyst (a cyst on the spinal cord, filled with spinal fluid)
Vitamin d deficiency
Abnormal dreams
Adverse event
Aggression

male:

Endotracheal intubation complication
Respiratory distress (difficulty in breathing)
Decreased appetite
Emotional disorder
Energy increased
Headache (pain in head)
Hospitalisation
Hypoxia (low oxygen in tissues)
Insomnia (sleeplessness)
Intentional self-injury

What are the common drug interactions of Lamotrigine and Xopenex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Endotracheal intubation complication
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Back pain
Headache (pain in head)
Hypoxia (low oxygen in tissues)
Vomiting

10-19:

Contusion (a type of hematoma of tissue in which capillaries)
Otitis externa (external ear infection)
Therapeutic response unexpected

20-29:

Sinusitis (inflammation of sinus)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Carotid artery aneurysm (a bulging or ballooning in the wall of a blood vessel)
Chronic kidney disease
Migraine (headache)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal failure (kidney dysfunction)

30-39:

Fibula fracture
Morning sickness (sickness in morning during pregnancy)
Hospitalisation
Internal hernia (protrusion of an intraperitoneal viscous into a compartment or under a constricting band within the abdominal cavity)
Memory impairment
Restless legs syndrome (a powerful urge to move your legs)
Sinusitis (inflammation of sinus)
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight decreased

40-49:

Blood pressure decreased
Chest pain
Dizziness
Panic attack
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)

50-59:

Depression
Drug ineffective
Fatigue (feeling of tiredness)
Heart rate increased
Idiosyncratic drug reaction (unusual effect of the medication)
Pruritus (severe itching of the skin)
Rash
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Swollen tongue (swelling of tongue)
Throat irritation

60+:

Adverse event
Cellulitis (infection under the skin)
Pneumonia
Surgery
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Infusion site irritation
Infusion site swelling
Local swelling (swelling at the site of some application of substance or injury)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 45 people, 56.25%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 27 people, 33.75%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 7.50%
Immunodeficiency Common Variable: 5 people, 6.25%
Nausea (feeling of having an urge to vomit): 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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