Lanoxin and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lanoxin (digoxin) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include arthritis among females and coma among males.

The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Bactrim ds. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

On Jul, 20, 2026

45 people who take Lanoxin and Bactrim ds together, and have interactions are studied.

Lanoxin and Bactrim ds drug interactions.

What are the common drug interactions of Lanoxin and Bactrim Ds, by gender? *:

female:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood alkaline phosphatase nos increased
Blood glucose decreased
Blood in stool
Blood lactate dehydrogenase increased
Blood uric acid increased
Cardiac death
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cardiomegaly (increased size of heart than normal)

male:

Coma (state of unconsciousness lasting more than six hours)
Cardiac failure congestive
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cushingoid (obesity and weakening of the muscles)
Death
Diarrhoea
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypercoagulation (increased tendency for clotting of the blood)
Hypertriglyceridaemia (excess of triglycerides in the blood)

What are the common drug interactions of Lanoxin and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Arrhythmia (irregular heartbeat)
Fatigue (feeling of tiredness)
Thrombocytopenia (decrease of platelets in blood)
Ventricular fibrillation (abnormally irregular heart rhythm)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Weight decreased
Diarrhoea
Pharyngolaryngeal pain
Cardiac death

40-49:

Aphthous stomatitis (mouth ulcer)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cushingoid (obesity and weakening of the muscles)
Diarrhoea
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Night sweats (sweating in night)
Pancreatitis (inflammation of pancreas)
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Sweat gland disorder

50-59:

Haemoglobin decreased
Headache (pain in head)
Hypertension (high blood pressure)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Influenza like illness
Intertrigo (inflammation (rash) of the body folds (adjacent areas of skin))
Lung disorder (lung disease)
Microalbuminuria (albumin into the urine)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)

60+:

Anaemia (lack of blood)
Renal failure (kidney dysfunction)
Atelectasis (partial or complete collapse of the lung)
Brain stem thrombosis (obstruction of a blood vessel by a blood clot in brain stem)
Cardiac arrest
Cardiac disorder
Cardiac failure
Cardiac failure congestive
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Hypercoagulation (increased tendency for clotting of the blood)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 11.11%
Pain: 5 people, 11.11%
Nausea (feeling of having an urge to vomit): 5 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.11%
High Blood Pressure: 4 people, 8.89%
Multiple Myeloma (cancer of the plasma cells): 4 people, 8.89%
Cardiac Failure Congestive: 4 people, 8.89%
Dizziness: 3 people, 6.67%
Blockage Of Leg Arteries: 3 people, 6.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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