Lanoxin and Diamox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lanoxin (digoxin) and Diamox (acetazolamide). Common drug interactions include gait disturbance among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Diamox. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Lanoxin?
Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.
What is Diamox?
Diamox has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 4,711 Diamox users. Check the latest studies of Diamox.
41 people who take Lanoxin and Diamox together, and have interactions are studied.

What are the common drug interactions of Lanoxin and Diamox, by gender? *:
female:
- Gait disturbance
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Blood glucose increased
- Cellulitis (infection under the skin)
- Hepatocellular damage (liver damage)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Iron deficiency anaemia
- Oedema (fluid collection in tissue)
- Postural hypotension
- Pyrexia (fever)
male:
- Dyspnoea (difficult or laboured respiration)
- Anorectal disorder
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Hepatic steatosis (fatty liver disease)
- Mass
- Nerve compression
- Neuropathy peripheral (surface nerve damage)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
What are the common drug interactions of Lanoxin and Diamox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Type 2 diabetes mellitus
50-59:
- Dysarthria (speech disorder)
- Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Gait disturbance
- Neuropathy peripheral (surface nerve damage)
- Arthralgia (joint pain)
- Atrial tachycardia (rhythm disturbance that arises in the atria)
- Back pain
- Cardiac tamponade (fluid accumulates in heart covering)
- Churg strauss syndrome (infection of small arteries and vein)
60+:
- Dyspnoea (difficult or laboured respiration)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Ascites (accumulation of fluid in the abdominal cavity)
- Blindness
- Blood cholesterol increased
- Blood triglycerides increased
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dehydration (dryness resulting from the removal of water)
What are the existing conditions these people have? *
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 9.76%
- Headache (pain in head): 4 people, 9.76%
- Body Temperature Increased: 4 people, 9.76%
- Pain: 4 people, 9.76%
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall): 4 people, 9.76%
- Nausea (feeling of having an urge to vomit): 4 people, 9.76%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 9.76%
- Joint Pain: 3 people, 7.32%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 7.32%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lanoxin and Diamox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lanoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diamox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lanoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diamox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and acetazolamide (the active ingredients of Lanoxin and Diamox, respectively), and Lanoxin and Diamox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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