Lanoxin and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lanoxin (digoxin) and Keppra (levetiracetam). Common drug interactions include overdose among females and encephalopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Keppra. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 13, 2026

100 people who take Lanoxin and Keppra together, and have interactions are studied.

What are the common drug interactions of Lanoxin and Keppra, by gender? *:

female:

Overdose
Pain
Anxiety
Asthenia (weakness)
Diarrhoea
Dysarthria (speech disorder)
Pneumonia
Dysphagia (a condition in which swallowing is difficult or painful)
Constipation
Depression

male:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypotension (abnormally low blood pressure)
Cervical vertebral fracture
Coma (state of unconsciousness lasting more than six hours)
Dehydration (dryness resulting from the removal of water)
Drug toxicity
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fall
Febrile neutropenia (fever with reduced white blood cells)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)

What are the common drug interactions of Lanoxin and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

n/a

30-39:

Abscess (pus)
Activities of daily living impaired
Agitation (state of anxiety or nervous excitement)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arrhythmia (irregular heartbeat)
Arteriosclerosis (thickening and hardening of arteries)
Arthropathy
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain

40-49:

Bladder disorder
Cardiac failure
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic foot
Dyspepsia (indigestion)
Hyperglycaemia (high blood sugar)
Loss of consciousness
Partial seizures (seizures which affect only a part of the brain at onset)

50-59:

Dysarthria (speech disorder)
Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Abscess limb (limb infection)
Cardiovascular disorder (heart diseases)
Cellulitis (infection under the skin)
Death
Perirectal abscess

60+:

Fatigue (feeling of tiredness)
Cardioactive drug level increased
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Nausea (feeling of having an urge to vomit)
Anxiety
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Constipation
Depression
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

What are the existing conditions these people have? *

High Blood Pressure: 18 people, 18.00%
Diabetes: 16 people, 16.00%
Post-Traumatic Epilepsy: 14 people, 14.00%
Gastritis (inflammation of stomach): 14 people, 14.00%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 14 people, 14.00%
Cardiac Disorder: 14 people, 14.00%
Cardiomyopathy (weakening of the heart muscle): 12 people, 12.00%
Pain: 11 people, 11.00%
Adjustment Disorder With Depressed Mood: 10 people, 10.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 7.00%

* Approximation only. Some reports may have incomplete information.

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