Lanoxin and Loratadine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lanoxin (digoxin) and Loratadine (loratadine). Common drug interactions include dyspnoea among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Loratadine. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.
What is Lanoxin?
Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.
What is Loratadine?
Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.
85 people who take Lanoxin and Loratadine together, and have interactions are studied.

What are the common drug interactions of Lanoxin and Loratadine, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Hypoaesthesia (reduced sense of touch or sensation)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Urinary retention (the inability to completely or partially empty the bladder)
- Urinary tract infection
- Cough
- Fatigue (feeling of tiredness)
- Hypotension (abnormally low blood pressure)
male:
- Dyspnoea (difficult or laboured respiration)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Cardiac failure
- Headache (pain in head)
- Akathisia (a movement disorder characterized by a feeling of inner restlessness)
- Anticoagulation drug level above therapeutic
- Asthenia (weakness)
- Balance disorder
- Chronic kidney disease
- Constipation
What are the common drug interactions of Lanoxin and Loratadine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood pressure increased
- Cold sweat
- Feeling jittery
- Headache (pain in head)
- Limb discomfort (discomfort in leg)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Vision blurred
30-39:
n/a
40-49:
- Epistaxis (bleed from the nose)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hepatomegaly (abnormal enlargement of the liver)
- International normalised ratio increased
- Liver fatty (fat deposition of liver)
- Loss of consciousness
50-59:
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Gait disturbance
- Hypoaesthesia (reduced sense of touch or sensation)
- Neuropathy peripheral (surface nerve damage)
- Cardiac failure
- Cough
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Dizziness
- Drug hypersensitivity
- Drug ineffective
60+:
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Cough
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Rash macular (small, flat red spots)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Arrhythmia (irregular heartbeat)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Diarrhoea
What are the existing conditions these people have? *
- Primary Myelofibrosis (primary disorder of the bone marrow): 7 people, 8.24%
- Dyspnea (difficult or laboured breathing): 6 people, 7.06%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 5.88%
- Pain: 5 people, 5.88%
- Nausea (feeling of having an urge to vomit): 5 people, 5.88%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 5.88%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Lanoxin and Loratadine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lanoxin (21,852 reports)
- Loratadine (56,314 reports)
Browse all drug interactions of Lanoxin and Loratadine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lanoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Loratadine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lanoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Loratadine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and loratadine (the active ingredients of Lanoxin and Loratadine, respectively), and Lanoxin and Loratadine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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