Lanoxin and Onglyza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lanoxin (digoxin) and Onglyza (saxagliptin hydrochloride). Common drug interactions include asthenia among females and colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Onglyza. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

What is Onglyza?

Onglyza has active ingredients of saxagliptin hydrochloride. It is often used in diabetes. eHealthMe is studying from 8,638 Onglyza users. Check the latest studies of Onglyza.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

12 people who take Lanoxin and Onglyza together, and have interactions are studied.

Lanoxin and Onglyza drug interactions.

What are the common drug interactions of Lanoxin and Onglyza, by gender? *:

female:

  1. Asthenia (weakness)
  2. Chronic kidney disease
  3. Dandruff
  4. Fall
  5. Fatigue (feeling of tiredness)
  6. Headache (pain in head)
  7. Hip fracture
  8. Oedema peripheral (superficial swelling)
  9. Pain in extremity
  10. Rash

male:

  1. Colitis (inflammation of colon)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Small intestinal obstruction (blockage in small intestine)
  4. Abdominal hernia
  5. Chronic kidney disease
  6. Blood sodium decreased
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  9. Renal failure (kidney dysfunction)

What are the common drug interactions of Lanoxin and Onglyza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Colitis (inflammation of colon)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  4. Oedema peripheral (superficial swelling)
  5. Pain in extremity
  6. Renal failure (kidney dysfunction)
  7. Urinary tract infection
  8. Small intestinal obstruction (blockage in small intestine)
  9. Abdominal hernia
  10. Arthralgia (joint pain)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 5 people, 41.67%
  2. High Blood Pressure: 5 people, 41.67%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 41.67%
  4. Hypertriglyceridaemia (excess of triglycerides in the blood): 3 people, 25.00%
  5. High Blood Cholesterol: 3 people, 25.00%
  6. Cardiomyopathy (weakening of the heart muscle): 3 people, 25.00%
  7. Pain: 2 people, 16.67%
  8. Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
  9. Insomnia (sleeplessness): 2 people, 16.67%
  10. Infection: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lanoxin and Onglyza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lanoxin and Onglyza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Onglyza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Onglyza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on digoxin and saxagliptin hydrochloride (the active ingredients of Lanoxin and Onglyza, respectively), and Lanoxin and Onglyza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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