Lanoxin and Periostat drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lanoxin (digoxin) and Periostat (doxycycline hyclate). Common drug interactions include anaemia among females and acute prerenal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Periostat. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Lanoxin?
Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.
What is Periostat?
Periostat has active ingredients of doxycycline hyclate. eHealthMe is studying from 273 Periostat users. Check the latest studies of Periostat.
19 people who take Lanoxin and Periostat together, and have interactions are studied.

What are the common drug interactions of Lanoxin and Periostat, by gender? *:
female:
- Anaemia (lack of blood)
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
male:
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Metastases to bone (cancer spreads to bone)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Nephrolithiasis (calculi in the kidneys)
- Neuropathy peripheral (surface nerve damage)
- Osteonecrosis of jaw (death of bone of jaw)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Upper respiratory tract infection
What are the common drug interactions of Lanoxin and Periostat, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaemia (lack of blood)
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
- Aortic arteriosclerosis (hardening of the aortic arteries)
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
50-59:
n/a
60+:
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Metastases to bone (cancer spreads to bone)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Nephrolithiasis (calculi in the kidneys)
- Neuropathy peripheral (surface nerve damage)
- Osteonecrosis of jaw (death of bone of jaw)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Upper respiratory tract infection
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%
- Hepatitis C: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Lanoxin and Periostat?
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- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lanoxin and Periostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lanoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Periostat:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lanoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Periostat and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and doxycycline hyclate (the active ingredients of Lanoxin and Periostat, respectively), and Lanoxin and Periostat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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