Lanoxin and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lanoxin (digoxin) and Questran (cholestyramine). Common drug interactions include pericarditis among females and cholelithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Questran. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.



On Jul, 29, 2026

50 people who take Lanoxin and Questran together, and have interactions are studied.

Lanoxin and Questran drug interactions.

What are the common drug interactions of Lanoxin and Questran, by gender? *:

female:

  1. Pericarditis (inflammation of the pericardium)
  2. Tracheitis (an inflammation of the trachea)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Dehydration (dryness resulting from the removal of water)
  5. Drug ineffective
  6. Ileus (a painful obstruction of the ileum or other part of the intestine)
  7. Alopecia (absence of hair from areas of the body)
  8. Anaemia (lack of blood)
  9. Anxiety
  10. Blood chloride decreased

male:

  1. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  2. Weight decreased
  3. Anxiety
  4. Constipation
  5. Foot ulcer
  6. Hepatocellular damage (liver damage)
  7. Hypokalaemia (low potassium)
  8. Injury
  9. Osteomyelitis (infection of bone)
  10. Renal failure (kidney dysfunction)

What are the common drug interactions of Lanoxin and Questran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cholecystitis acute (rapid infection of gallbladder)
  2. Abdominal pain
  3. Tracheitis (an inflammation of the trachea)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Dehydration (dryness resulting from the removal of water)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood chloride decreased
  2. Chest pain
  3. Dehydration (dryness resulting from the removal of water)
  4. Hypokalaemia (low potassium)
  5. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  6. Hypotension (abnormally low blood pressure)
  7. Nausea (feeling of having an urge to vomit)
  8. Pneumonia
  9. Retching (strong involuntary effort to vomit)
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

  1. Blood in stool
  2. Cardiac failure congestive
  3. Cardiomegaly (increased size of heart than normal)
  4. Chest pain
  5. Cholecystitis (infection of gallbladder)
  6. Cholecystitis acute (rapid infection of gallbladder)
  7. Chronic obstructive airways disease
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Cyst (a closed sac)
  10. Dehydration (dryness resulting from the removal of water)

60+:

  1. Weight decreased
  2. Myalgia (muscle pain)
  3. Hepatocellular damage (liver damage)
  4. Hypokalaemia (low potassium)
  5. Osteomyelitis (infection of bone)
  6. Pain
  7. Skin amp subcutaneous tissue abscess (infection of the skin and subcutaneous tissue)
  8. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  9. Weakness
  10. Abdominal pain

What are the existing conditions these people have? *

  1. Pain: 4 people, 8.00%
  2. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 6.00%
  3. Diabetes: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lanoxin and Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Questran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Questran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on digoxin and cholestyramine (the active ingredients of Lanoxin and Questran, respectively), and Lanoxin and Questran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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