Lanoxin and Tessalon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lanoxin (digoxin) and Tessalon (benzonatate). Common drug interactions include pyrexia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Tessalon. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

What is Tessalon?

Tessalon has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 6,493 Tessalon users. Check the latest studies of Tessalon.



On Jul, 04, 2026

63 people who take Lanoxin and Tessalon together, and have interactions are studied.

Lanoxin and Tessalon drug interactions.

What are the common drug interactions of Lanoxin and Tessalon, by gender? *:

female:

  1. Pyrexia (fever)
  2. Cardiac failure congestive
  3. Diarrhoea
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  6. Headache (pain in head)
  7. Influenza
  8. Oedema peripheral (superficial swelling)
  9. Oropharyngeal pain
  10. Renal failure (kidney dysfunction)

male:

  1. Pneumonia
  2. Asthenia (weakness)
  3. Anaemia (lack of blood)
  4. Anxiety
  5. Apnoea (suspension of external breathing)
  6. Arthralgia (joint pain)
  7. Back pain
  8. Bone disorder
  9. Bone pain
  10. Bronchial secretion retention

What are the common drug interactions of Lanoxin and Tessalon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaemia of chronic disease
  2. Blood culture positive
  3. Cardiac murmur (an heart sound in valve abnormality)
  4. Catheter site infection (infection at the site of insertion)
  5. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  6. Dyspnoea (difficult or laboured respiration)
  7. Headache (pain in head)
  8. Influenza
  9. Mycobacterium avium complex infection
  10. Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

n/a

50-59:

  1. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  2. Ejection fraction decreased (systolic heart failure)
  3. Fall
  4. Hypertension (high blood pressure)
  5. Joint effusion (presence of extra fluid in joint covering)
  6. Oedema peripheral (superficial swelling)
  7. Oropharyngeal pain
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Pain
  10. Pain in jaw

60+:

  1. Pneumonia
  2. Asthenia (weakness)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Pyrexia (fever)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Unresponsive to stimuli
  7. Anxiety
  8. Apnoea (suspension of external breathing)
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 22 people, 34.92%
  2. High Blood Pressure: 7 people, 11.11%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 9.52%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 9.52%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 7.94%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 7.94%
  7. Fatigue (feeling of tiredness): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

Do you take Lanoxin and Tessalon?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lanoxin and Tessalon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lanoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tessalon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lanoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tessalon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on digoxin and benzonatate (the active ingredients of Lanoxin and Tessalon, respectively), and Lanoxin and Tessalon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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