Lantus and A-hydrocort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lantus (insulin glargine recombinant) and A-hydrocort (hydrocortisone sodium succinate). Common drug interactions include renal failure among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Lantus and A-hydrocort. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

What is A-hydrocort?

A-hydrocort has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 636 A-hydrocort users. Check the latest studies of A-hydrocort.

On Jul, 13, 2026

15 people who take Lantus and A-hydrocort together, and have interactions are studied.

Lantus and A-hydrocort drug interactions.

What are the common drug interactions of Lantus and A-Hydrocort, by gender? *:

female:

Renal failure (kidney dysfunction)
Chronic kidney disease
Fall
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Psoriasis (immune-mediated disease that affects the skin)
Renal injury (kidney injury)
Anaemia (lack of blood)
Depressed mood
Dermatitis infected (inflammation of the skin due to infection)
Injection site bruising

male:

Rash
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Fluid overload (too much fluid in the blood)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperhidrosis (abnormally increased sweating)
Immune system disorder
Malaise (a feeling of general discomfort or uneasiness)
Mouth ulceration (mouth ulcers)
Myalgia (muscle pain)
Nervousness

What are the common drug interactions of Lantus and A-Hydrocort, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Malaise (a feeling of general discomfort or uneasiness)

20-29:

n/a

30-39:

n/a

40-49:

Rash
Asthenia (weakness)
Chest discomfort
Hyperhidrosis (abnormally increased sweating)
Myalgia (muscle pain)
Nervousness
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Skin burning sensation

50-59:

Behcet's syndrome (involves inflammation of the blood vessels)
Blood cortisol decreased
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Immune system disorder
Mouth ulceration (mouth ulcers)
Oesophageal candidiasis (fungal infection of oesophagus)
Rash
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

60+:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Myopathy (a muscular disease in which the muscle fibres do not function)
Nephrogenic anaemia (anaemia due to kidney disease)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Pneumonia
Renal artery stenosis (narrowing of renal artery)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
High Blood Pressure: 3 people, 20.00%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 20.00%
High Blood Cholesterol: 3 people, 20.00%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 13.33%
Asthma: 1 person, 6.67%
Atherosclerosis (disorder of the arteries): 1 person, 6.67%
Bacterial Infection: 1 person, 6.67%
Behcet's Syndrome (involves inflammation of the blood vessels): 1 person, 6.67%
Blood Cortisol Abnormal: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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