Lantus and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lantus (insulin glargine recombinant) and Buscopan (hyoscine butylbromide). Common drug interactions include leukocytosis among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lantus and Buscopan. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

31 people who take Lantus and Buscopan together, and have interactions are studied.

What are the common drug interactions of Lantus and Buscopan, by gender? *:

female:

Leukocytosis (increased white blood cells)
Liver disorder (liver diseases)
Maternal exposure during pregnancy (use of substance during pregnancy)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Onychoclasis (breaking of the nails)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Ovarian cyst (fluid filled sac of the ovary)
Pain in extremity

male:

Febrile neutropenia (fever with reduced white blood cells)
Anaemia (lack of blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Pyrexia (fever)
Arthralgia (joint pain)
Blood pressure increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)

What are the common drug interactions of Lantus and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Sluggishness (lacking alertness)
Drug ineffective
Abasia (inability to walk)
Abdominal pain upper
Choking sensation (feeling of obstruction in respiratory system)
Erythema (redness of the skin)
Feeling hot
Gastric disorder (disease of stomach)
Hyperglycaemia (high blood sugar)
Hyperhidrosis (abnormally increased sweating)

40-49:

Cushing's syndrome (obesity, a rounded face, increased fat)
Injection site haematoma (localized swelling filled with blood at injection site)
Injection site pain
Pyrexia (fever)
Vomiting
Arthralgia (joint pain)
Blood pressure increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea

50-59:

Abasia (inability to walk)
Application site discolouration
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dysuria (painful or difficult urination)
Joint swelling
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pain in extremity
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Urinary tract infection

60+:

Febrile neutropenia (fever with reduced white blood cells)
Anaemia (lack of blood)
Hyperglycaemia (high blood sugar)
Pneumonia
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Abdominal pain
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood lactate dehydrogenase increased

What are the existing conditions these people have? *

Type 2 Diabetes: 7 people, 22.58%
Pain: 7 people, 22.58%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 12.90%
Lactose Intolerance (inability to digest lactose): 4 people, 12.90%
Dysmenorrhea (painful menstruation): 4 people, 12.90%
Diarrhea: 3 people, 9.68%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 9.68%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 9.68%
Bladder Cancer: 3 people, 9.68%
Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 3 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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