Lantus and Nyquil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lantus (insulin glargine recombinant) and Nyquil (acetaminophen / dextromethorphan / doxylamine / pseudoephedrine). Common drug interactions include weight decreased among females and nasal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Lantus and Nyquil. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

What is Nyquil?

Nyquil has active ingredients of acetaminophen / dextromethorphan / doxylamine / pseudoephedrine. It is often used in cold symptoms. eHealthMe is studying from 2,240 Nyquil users. Check the latest studies of Nyquil.



On Aug, 01, 2026

16 people who take Lantus and Nyquil together, and have interactions are studied.

Lantus and Nyquil drug interactions.

What are the common drug interactions of Lantus and Nyquil, by gender? *:

female:

  1. Weight decreased
  2. Chronic kidney disease
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Renal failure (kidney dysfunction)
  5. Alopecia (absence of hair from areas of the body)
  6. Angioedema (rapid swelling of the dermis)
  7. Ankylosing spondylitis (type of arthritis affecting the spine)
  8. Arthralgia (joint pain)
  9. Blood glucose increased
  10. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

male:

  1. Nasal disorder (diseases of nose)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Hot flush (sudden feelings of heat)
  4. Hydrocephalus (water on the brain)
  5. Incontinence (lack of moderation or self-control)
  6. Insomnia (sleeplessness)
  7. Localised infection (infection at the single location)
  8. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  9. Penile size reduced
  10. Respiratory disorder (respiratory disease)

What are the common drug interactions of Lantus and Nyquil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Alopecia (absence of hair from areas of the body)
  2. Psychological trauma

40-49:

  1. Nasal disorder (diseases of nose)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Chronic kidney disease
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Renal failure (kidney dysfunction)
  6. Headache (pain in head)

50-59:

n/a

60+:

  1. Blood glucose increased
  2. Arthralgia (joint pain)
  3. Insomnia (sleeplessness)
  4. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  5. Penile size reduced
  6. Asthenia (weakness)
  7. Blood urine present
  8. Endophthalmitis (inflammation of the internal coats of the eye)
  9. Eructation (release of gas from the digestive tract)
  10. Fall

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 25.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 18.75%
  3. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 12.50%
  4. Sleep Disorder: 2 people, 12.50%
  5. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 12.50%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
  7. Fever: 1 person, 6.25%
  8. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 6.25%
  9. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 6.25%
  10. Diabetes Mellitus Inadequate Control: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Lantus and Nyquil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lantus and Nyquil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lantus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nyquil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lantus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nyquil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on insulin glargine recombinant and acetaminophen / dextromethorphan / doxylamine / pseudoephedrine (the active ingredients of Lantus and Nyquil, respectively), and Lantus and Nyquil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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