Lantus and Perphenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lantus (insulin glargine recombinant) and Perphenazine (perphenazine). Common drug interactions include knee arthroplasty among females and gait disturbance among males.

The phase IV clinical study analyzes what interactions people have when they take Lantus and Perphenazine. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

What is Perphenazine?

Perphenazine has active ingredients of perphenazine. It is often used in bipolar i disorder. eHealthMe is studying from 2,712 Perphenazine users. Check the latest studies of Perphenazine.

On Jul, 13, 2026

30 people who take Lantus and Perphenazine together, and have interactions are studied.

Lantus and Perphenazine drug interactions.

What are the common drug interactions of Lantus and Perphenazine, by gender? *:

female:

Knee arthroplasty
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Oedema peripheral (superficial swelling)
Proctitis (inflammation of the rectum and anus)
Vomiting
Abdominal pain upper
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Aortic valve incompetence

male:

Gait disturbance
Dyspnoea (difficult or laboured respiration)
Breath odour
Breath sounds
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebral atrophy (decrement in size of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased activity

What are the common drug interactions of Lantus and Perphenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus inadequate control
Gait disturbance
Muscular weakness (muscle weakness)
Narcissistic personality disorder (a personality disorder in which the individual is described as being excessively preoccupied with issues of personal)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Psoriasis (immune-mediated disease that affects the skin)
Scab (a hard coating on the skin formed during the wound healing)
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Skin disorder (skin disease)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Confusional state
Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting
Anuria (failure of the kidneys to produce urine)
Blood glucose increased
Diabetes with hyperosmolarity (diabetes with increasing blood glucose levels and dehydration)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

50-59:

Oedema peripheral (superficial swelling)
Oral disorder (mouth disease)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteomyelitis (infection of bone)
Pain in extremity
Pain in jaw
Pleural effusion (water on the lungs)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Purulence (containing pus)

60+:

Dyspnoea (difficult or laboured respiration)
Cardiac failure congestive
Inflammatory bowel disease
Injection site bruising
Injection site haematoma (localized swelling filled with blood at injection site)
Knee arthroplasty
Oedema peripheral (superficial swelling)
Proctitis (inflammation of the rectum and anus)
Abdominal pain upper
Akathisia (a movement disorder characterized by a feeling of inner restlessness)

What are the existing conditions these people have? *

Pain: 8 people, 26.67%
Metastases To Bone (cancer spreads to bone): 8 people, 26.67%
Type 2 Diabetes: 7 people, 23.33%
High Blood Pressure: 3 people, 10.00%
Type 1 Diabetes: 2 people, 6.67%
Tardive Dyskinesia (a disorder that involves involuntary movements): 2 people, 6.67%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.67%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 6.67%
Depression: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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