Latisse and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Latisse (bimatoprost) and Melatonin (melatonin). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Latisse and Melatonin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Latisse?

Latisse has active ingredients of bimatoprost. eHealthMe is studying from 12,172 Latisse users. Check the latest studies of Latisse.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.



On Jul, 10, 2026

20 people who take Latisse and Melatonin together, and have interactions are studied.

Latisse and Melatonin drug interactions.

What are the common drug interactions of Latisse and Melatonin, by gender? *:

female:

  1. Drug ineffective
  2. Disability
  3. Migraine (headache)
  4. Muscle spasms (muscle contraction)
  5. Osteomyelitis (infection of bone)
  6. Pain in extremity
  7. Restless legs syndrome (a powerful urge to move your legs)
  8. Spinal fusion surgery
  9. Staphylococcal infection (an infection with staphylococcus bacteria)
  10. Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)

male:

n/a

What are the common drug interactions of Latisse and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Asthenia (weakness)
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  4. Erythema (redness of the skin)
  5. Fatigue (feeling of tiredness)
  6. Fluid retention (an abnormal accumulation of fluid in the blood)
  7. Headache (pain in head)
  8. Hunger
  9. Loss of consciousness
  10. Migraine (headache)

50-59:

  1. Myalgia (muscle pain)
  2. Osteomyelitis (infection of bone)
  3. Pain in extremity
  4. Restless legs syndrome (a powerful urge to move your legs)
  5. Spinal fusion surgery
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Anxiety
  8. Application site erosion
  9. Application site erythema (redness of the skin at application site)
  10. Application site irritation

60+:

  1. Blood cholesterol increased
  2. Drug ineffective

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 60.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 50.00%
  3. Growth Of Eyelashes: 4 people, 20.00%
  4. Sleep Disorder: 3 people, 15.00%
  5. Hypersensitivity: 2 people, 10.00%
  6. Dry Eyes (lack of adequate tears): 2 people, 10.00%
  7. Fatigue (feeling of tiredness): 2 people, 10.00%
  8. High Blood Pressure: 2 people, 10.00%
  9. Drowsiness: 1 person, 5.00%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Latisse and Melatonin?

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- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Latisse and Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Latisse:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Latisse and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melatonin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bimatoprost and melatonin (the active ingredients of Latisse and Melatonin, respectively), and Latisse and Melatonin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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