Latuda and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Latuda (lurasidone hydrochloride) and Aricept (donepezil hydrochloride). Common drug interactions include fall among females and bone density decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Latuda and Aricept. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Latuda?

Latuda has active ingredients of lurasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 21,543 Latuda users. Check the latest studies of Latuda.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

24 people who take Latuda and Aricept together, and have interactions are studied.

What are the common drug interactions of Latuda and Aricept, by gender? *:

female:

Fall
Infection
Fatigue (feeling of tiredness)
Muscular weakness (muscle weakness)
Pain in extremity
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Balance disorder
Blindness
Chest pain
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

male:

Bone density decreased
Bone loss
Chronic kidney disease
Emotional disorder
Fracture
Granulocytopenia (lack of granulocyte)
Knee arthroplasty
Leukopenia (less number of white blood cells in blood)
Osteonecrosis (death of bone)
Tooth loss

What are the common drug interactions of Latuda and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bone density decreased
Bone loss
Chronic kidney disease
Emotional disorder
Fracture
Knee arthroplasty
Osteonecrosis (death of bone)
Tooth loss

50-59:

n/a

60+:

Fall
Fatigue (feeling of tiredness)
Abulia (lack of will or initiative)
Communication disorder (speech and language disorder)
Hydrocephalus (water on the brain)
Personality disorder
Psychotic disorder
Abdominal neoplasm (cancer of the stomach)
Agitation (state of anxiety or nervous excitement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 29.17%
Tardive Dyskinesia (a disorder that involves involuntary movements): 5 people, 20.83%
Depression: 5 people, 20.83%
Stress And Anxiety: 4 people, 16.67%
Memory Loss: 3 people, 12.50%
Insomnia (sleeplessness): 3 people, 12.50%
High Blood Pressure: 3 people, 12.50%
Psychotic Disorder: 2 people, 8.33%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 2 people, 8.33%
Pain: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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