Latuda and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Latuda (lurasidone hydrochloride) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include abdominal discomfort among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Latuda and Valacyclovir. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Latuda?

Latuda has active ingredients of lurasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 21,543 Latuda users. Check the latest studies of Latuda.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 21, 2026

55 people who take Latuda and Valacyclovir together, and have interactions are studied.

Latuda and Valacyclovir drug interactions.

What are the common drug interactions of Latuda and Valacyclovir, by gender? *:

female:

  1. Abdominal discomfort
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Constipation
  4. Disability
  5. Intervertebral disc protrusion (spinal disc protrusion)
  6. Drug ineffective
  7. Chronic kidney disease
  8. Pain
  9. Apnoea (suspension of external breathing)
  10. Weight decreased

male:

  1. Abdominal pain
  2. Diarrhoea
  3. Eye pain
  4. Chronic kidney disease
  5. Dry eye (lack of adequate tears)
  6. Eye swelling
  7. Fatigue (feeling of tiredness)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Latuda and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Weight increased

20-29:

  1. Drug dependence
  2. Dry eye (lack of adequate tears)
  3. Eye pain
  4. Hallucination (an experience involving the perception of something not present)
  5. Hallucination, auditory (perceiving sounds without auditory stimulus)
  6. Muscle twitching
  7. Pain in jaw
  8. Psychotic behaviour
  9. Rash
  10. Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)

30-39:

  1. Maternal exposure during pregnancy (use of substance during pregnancy)
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  4. Chronic kidney disease
  5. Fluid retention (an abnormal accumulation of fluid in the blood)
  6. Hypoaesthesia (reduced sense of touch or sensation)

40-49:

  1. Pain
  2. Constipation
  3. Headache (pain in head)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Weight decreased
  6. Anxiety
  7. Emotional distress
  8. Abdominal discomfort
  9. Abdominal pain upper
  10. Arthralgia (joint pain)

50-59:

  1. Chronic kidney disease
  2. Drug ineffective
  3. Nausea (feeling of having an urge to vomit)
  4. Renal failure (kidney dysfunction)
  5. Vomiting

60+:

  1. Joint stiffness
  2. Myalgia (muscle pain)
  3. Disability
  4. Drug hypersensitivity
  5. Heart rate decreased
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Hospitalisation
  8. Intervertebral disc protrusion (spinal disc protrusion)
  9. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  10. Muscular weakness (muscle weakness)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 28 people, 50.91%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 30.91%
  3. Pain: 4 people, 7.27%
  4. Drowsiness: 4 people, 7.27%
  5. Migraine (headache): 3 people, 5.45%
  6. Hiv Infection: 3 people, 5.45%
  7. High Blood Pressure: 3 people, 5.45%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.45%
  9. Depression: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Latuda and Valacyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Latuda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valacyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Latuda and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valacyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lurasidone hydrochloride and valacyclovir hydrochloride (the active ingredients of Latuda and Valacyclovir, respectively), and Latuda and Valacyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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