Leflunomide and Cilostazol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leflunomide (leflunomide) and Cilostazol (cilostazol). Common drug interactions include septic shock among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Leflunomide and Cilostazol. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Cilostazol?

Cilostazol has active ingredients of cilostazol. It is often used in arteriosclerosis of the extremities. eHealthMe is studying from 7,877 Cilostazol users. Check the latest studies of Cilostazol.

On Jul, 17, 2026

42 people who take Leflunomide and Cilostazol together, and have interactions are studied.

Leflunomide and Cilostazol drug interactions.

What are the common drug interactions of Leflunomide and Cilostazol, by gender? *:

female:

Septic shock (shock due to blood infection)
Somnolence (a state of near-sleep, a strong desire for sleep)
Concussion (short loss of normal brain function in response to a head injury)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dry gangrene (diminished blood supply due to vascular problems)
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gait disturbance
Gastric disorder (disease of stomach)
Gastrointestinal infection (infection of stomach and intestine)

male:

Arthralgia (joint pain)
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Irritability
Neuralgia (pain in one or more nerves)
Death
Ankylosing spondylitis (type of arthritis affecting the spine)
Drug ineffective
Ingrown hair
Ligament sprain (ligament stretched)
Pain

What are the common drug interactions of Leflunomide and Cilostazol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Back pain
Dry gangrene (diminished blood supply due to vascular problems)
Gastric disorder (disease of stomach)
Syncope (loss of consciousness with an inability to maintain postural tone)

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Sinusitis (inflammation of sinus)
Weight increased
Weight loss poor
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Gallbladder disorder
Hypertension (high blood pressure)
Nasopharyngitis (inflammation of the nasopharynx)
Poor venous access
Back pain

50-59:

Arthralgia (joint pain)
Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
Impaired fasting glucose
Latent tuberculosis (hidden tuberculosis)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rash erythematous (redness of the skin)
Skin plaque (red, scaly patches to appear on the skin)
Asthenia (weakness)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Joint lock

60+:

Insomnia (sleeplessness)
Arthralgia (joint pain)
Back pain
Bacterial infection
Balance disorder
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Contusion (a type of hematoma of tissue in which capillaries)
Death
Eczema nummular (circular or oval patches of eczema with well-defined edges)
Fall

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 33.33%
Stable Angina (a constant chest pain): 7 people, 16.67%
Pain: 7 people, 16.67%
Heart Disease: 6 people, 14.29%
Takayasu's Arteritis (an inflammation of the aorta -- the artery that carries blood from the heart to the rest of the body): 5 people, 11.90%
Osteoporosis (bones weak and more likely to break): 4 people, 9.52%
Migraine (headache): 4 people, 9.52%
Insomnia (sleeplessness): 4 people, 9.52%
Thyroid Diseases: 3 people, 7.14%
Psychotic Disorder Due To A General Medical Condition: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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