Leflunomide and Fluocinonide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leflunomide (leflunomide) and Fluocinonide (fluocinonide). Common drug interactions include skin disorder among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Leflunomide and Fluocinonide. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Fluocinonide?

Fluocinonide has active ingredients of fluocinonide. It is often used in eczema. eHealthMe is studying from 6,385 Fluocinonide users. Check the latest studies of Fluocinonide.

On Jul, 12, 2026

79 people who take Leflunomide and Fluocinonide together, and have interactions are studied.

Leflunomide and Fluocinonide drug interactions.

What are the common drug interactions of Leflunomide and Fluocinonide, by gender? *:

female:

Skin disorder (skin disease)
Spinal fracture (fracture in one of vertebrae)
Thrombosis (formation of a blood clot inside a blood vessel)
Upper respiratory tract infection
Anaemia of chronic disease
Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Abdominal discomfort
Abdominal pain

male:

Asthenia (weakness)
Blood pressure fluctuation
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory tract congestion (blockage on respiratory system)
Skin infection
Weight decreased
Arthralgia (joint pain)
Dizziness
Headache (pain in head)

What are the common drug interactions of Leflunomide and Fluocinonide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective

30-39:

Arthropathy
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Rash
Anaemia of chronic disease
Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Ankylosing spondylitis (type of arthritis affecting the spine)

40-49:

Rash generalised (rash on most of body parts)
Drug ineffective
Diarrhoea
Dry skin
Hidradenitis (chronic disease of a type of sweat gland)
Nausea (feeling of having an urge to vomit)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Arthralgia (joint pain)
Abdominal discomfort
Asthma

50-59:

Bladder transitional cell carcinoma (types of bladder cancer)
Cardiac failure congestive
Cellulitis (infection under the skin)
Pneumonia
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Abdominal pain
Adverse drug reaction
Back pain
Depression

60+:

Pain
Arthralgia (joint pain)
Lung disorder (lung disease)
Obstruction
Parkinson's disease
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Respiratory tract congestion (blockage on respiratory system)
Skin infection
Weight decreased

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 9 people, 11.39%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 10.13%
Immunodeficiency Common Variable: 7 people, 8.86%
Osteoporosis (bones weak and more likely to break): 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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