Leflunomide and Memantine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leflunomide (leflunomide) and Memantine (memantine). Common drug interactions include chronic obstructive pulmonary disease among females and hospitalisation among males.

The phase IV clinical study analyzes what interactions people have when they take Leflunomide and Memantine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Leflunomide?

Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.

On Jul, 25, 2026

21 people who take Leflunomide and Memantine together, and have interactions are studied.

Leflunomide and Memantine drug interactions.

What are the common drug interactions of Leflunomide and Memantine, by gender? *:

female:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Ear infection
Hospitalisation
Urinary tract infection
Breath holding
Diarrhoea
Infection
Injection site vesicles (fluid- or air-filled cavity or sac at injection site)
Oedema (fluid collection in tissue)
Pain

male:

Hospitalisation
Inappropriate affect
Aggression
Arthralgia (joint pain)
Back pain
Blindness
Delusion (a false belief or opinion)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug ineffective

What are the common drug interactions of Leflunomide and Memantine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Hospitalisation
Inappropriate affect
Memory impairment
Oedema (fluid collection in tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Aggression
Arthralgia (joint pain)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 28.57%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 19.05%
Psychotic Disorder Due To A General Medical Condition: 3 people, 14.29%
Parkinson's Disease: 3 people, 14.29%
Pain: 3 people, 14.29%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 14.29%
Sleep Disorder: 2 people, 9.52%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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