Leflunomide and Timolol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Leflunomide (leflunomide) and Timolol (timolol). Common drug interactions include cardio-respiratory arrest among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Leflunomide and Timolol. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Leflunomide?
Leflunomide has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 82,105 Leflunomide users. Check the latest studies of Leflunomide.
What is Timolol?
Timolol has active ingredients of timolol. It is often used in glaucoma. eHealthMe is studying from 9,142 Timolol users. Check the latest studies of Timolol.
34 people who take Leflunomide and Timolol together, and have interactions are studied.

What are the common drug interactions of Leflunomide and Timolol, by gender? *:
female:
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Diarrhoea
- Escherichia sepsis (bacterial infection by escherichia coli)
- Hypertension (high blood pressure)
- Renal failure (kidney dysfunction)
- Laryngeal disorder (disease of larynx related to voice)
- Drug ineffective
- Drug intolerance (drug sensitivity)
- Abdominal discomfort
- Blood pressure increased
male:
- Arthralgia (joint pain)
- Back pain
- Weight decreased
- Asthenia (weakness)
- Bladder disorder
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cataract (clouding of the lens inside the eye)
- Cerebrospinal fluid leakage
- Dental caries
- Eye haemorrhage (bleeding in the eye)
What are the common drug interactions of Leflunomide and Timolol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Intraocular pressure increased
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Hypertension (high blood pressure)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Drug intolerance (drug sensitivity)
- Intervertebral disc degeneration (spinal disc degeneration)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Injection site bruising
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Psoriasis (immune-mediated disease that affects the skin)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Abdominal discomfort
What are the existing conditions these people have? *
- Polychondritis (progressive inflammation of cartilage and other connective tissue): 11 people, 32.35%
- Dry Eyes (lack of adequate tears): 10 people, 29.41%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 11.76%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Leflunomide and Timolol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Leflunomide (82,105 reports)
- Timolol (9,142 reports)
Browse all drug interactions of Leflunomide and Timolol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Leflunomide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Timolol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Leflunomide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Timolol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on leflunomide and timolol (the active ingredients of Leflunomide and Timolol, respectively), and Leflunomide and Timolol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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