Lenalidomide and Levothroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lenalidomide (lenalidomide) and Levothroid (levothyroxine sodium). Common drug interactions include diarrhoea among females and diabetic ketoacidosis among males.

The phase IV clinical study analyzes what interactions people have when they take Lenalidomide and Levothroid. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.



On Jul, 16, 2026

23 people who take Lenalidomide and Levothroid together, and have interactions are studied.

Lenalidomide and Levothroid drug interactions.

What are the common drug interactions of Lenalidomide and Levothroid, by gender? *:

female:

  1. Diarrhoea
  2. Anaemia (lack of blood)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Blood creatinine increased
  7. Confusional state
  8. Decreased appetite
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Dehydration (dryness resulting from the removal of water)

male:

  1. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  2. Septic shock (shock due to blood infection)
  3. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pneumonia
  6. Rash
  7. Thrombosis (formation of a blood clot inside a blood vessel)
  8. White blood cell count decreased
  9. Acne (skin problems that cause pimples)
  10. Cardiac amyloidosis (protein deposition in heart)

What are the common drug interactions of Lenalidomide and Levothroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Thrombosis (formation of a blood clot inside a blood vessel)
  2. Cardiac amyloidosis (protein deposition in heart)
  3. Muscular weakness (muscle weakness)

50-59:

  1. Diarrhoea
  2. White blood cell count decreased
  3. Ear infection
  4. Eye infection
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Upper respiratory tract infection
  7. Urinary tract infection

60+:

  1. Anaemia (lack of blood)
  2. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  3. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  4. Dehydration (dryness resulting from the removal of water)
  5. Diarrhoea
  6. Dry mouth
  7. Dyspnoea (difficult or laboured respiration)
  8. Exfoliative rash (scaly red generalized skin rash)
  9. Faeces discoloured
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 15 people, 65.22%
  2. Pain: 5 people, 21.74%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 8.70%
  4. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 8.70%
  5. High Blood Pressure: 2 people, 8.70%
  6. Cough: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Lenalidomide and Levothroid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lenalidomide and Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lenalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levothroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide and levothyroxine sodium (the active ingredients of Lenalidomide and Levothroid, respectively), and Lenalidomide and Levothroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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