Lenalidomide and Nplate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lenalidomide (lenalidomide) and Nplate (romiplostim). Common drug interactions include diverticulum intestinal among females and haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Lenalidomide and Nplate. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Lenalidomide?
Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.
What is Nplate?
Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
19 people who take Lenalidomide and Nplate together, and have interactions are studied.

What are the common drug interactions of Lenalidomide and Nplate, by gender? *:
female:
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
- Extramedullary haemopoiesis (hematopoiesis occurring outside of the medulla of the bone)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Nephrolithiasis (calculi in the kidneys)
- Pleural effusion (water on the lungs)
- Pyrexia (fever)
- Splenic infarction (tissue damage of spleen)
- Splenomegaly (enlargement of spleen)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Weight decreased
male:
- Haemorrhage (bleeding)
- Multiple myeloma (cancer of the plasma cells)
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
- Pneumonia
- Thrombocytopenia (decrease of platelets in blood)
What are the common drug interactions of Lenalidomide and Nplate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
- Therapeutic response decreased (less preventive response)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Nephrolithiasis (calculi in the kidneys)
- Pleural effusion (water on the lungs)
- Pyrexia (fever)
- Splenic infarction (tissue damage of spleen)
- Splenomegaly (enlargement of spleen)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Weight decreased
What are the existing conditions these people have? *
- Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 18 people, 94.74%
- Thrombocytopenia (decrease of platelets in blood): 3 people, 15.79%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 15.79%
- Nausea (feeling of having an urge to vomit): 1 person, 5.26%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Lenalidomide and Nplate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lenalidomide (52,881 reports)
- Nplate (17,850 reports)
Browse all drug interactions of Lenalidomide and Nplate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lenalidomide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nplate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lenalidomide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nplate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lenalidomide and romiplostim (the active ingredients of Lenalidomide and Nplate, respectively), and Lenalidomide and Nplate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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