Lenalidomide and Valproic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lenalidomide (lenalidomide) and Valproic acid (valproic acid). Common drug interactions include cardiac arrest among females and leukopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lenalidomide and Valproic acid. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.

What is Valproic acid?

Valproic acid has active ingredients of valproic acid. It is often used in epilepsy. eHealthMe is studying from 36,193 Valproic acid users. Check the latest studies of Valproic acid.

On Aug, 03, 2026

18 people who take Lenalidomide and Valproic acid together, and have interactions are studied.

Lenalidomide and Valproic acid drug interactions.

What are the common drug interactions of Lenalidomide and Valproic Acid, by gender? *:

female:

Cardiac arrest
Pulmonary sepsis (pus in lungs)

male:

Leukopenia (less number of white blood cells in blood)
Anaemia (lack of blood)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Coronary angioplasty
Depression
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dysgeusia (disorder of the sense of taste)

What are the common drug interactions of Lenalidomide and Valproic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alopecia (absence of hair from areas of the body)
Anticonvulsant drug level increased
Conjunctivitis (pink eye)
Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
Radiation skin injury

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Immunosuppression
Jc virus infection
Paresis (a condition of muscular weakness)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Back pain

60+:

Leukopenia (less number of white blood cells in blood)
Nasopharyngitis (inflammation of the nasopharynx)
Tremor (trembling or shaking movements in one or more parts of your body)
Anaemia (lack of blood)
Bacterial infection
Death
Dysarthria (speech disorder)
Gastrointestinal neoplasm (cancer tumour of digestive tract)
Joint swelling
Microangiopathic haemolytic anaemia (anaemia due to inability of bone marrow to compensate the premature destruction of red blood cells)

What are the existing conditions these people have? *

Sleep Disorder: 8 people, 44.44%
Multiple Myeloma (cancer of the plasma cells): 7 people, 38.89%
Tumor: 3 people, 16.67%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 11.11%
Bone Marrow Tumor Cell Infiltration: 2 people, 11.11%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 5.56%
Progressive Multifocal Leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 1 person, 5.56%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 5.56%
Malignant Neoplasm Progression (cancer tumour came back): 1 person, 5.56%
High Blood Cholesterol: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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