Lescol and Hydramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lescol (fluvastatin sodium) and Hydramine (diphenhydramine hydrochloride). Common drug interactions include injury among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Lescol and Hydramine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Lescol?

Lescol has active ingredients of fluvastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 7,306 Lescol users. Check the latest studies of Lescol.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.



On Aug, 06, 2026

17 people who take Lescol and Hydramine together, and have interactions are studied.

Lescol and Hydramine drug interactions.

What are the common drug interactions of Lescol and Hydramine, by gender? *:

female:

  1. Injury
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Osteonecrosis (death of bone)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Pain
  6. Pain in jaw
  7. Spinal osteoarthritis (joint cartilage loss in spine)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Aortic arteriosclerosis (hardening of the aortic arteries)
  10. Bone density decreased

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety
  3. Pyrexia (fever)
  4. Rash morbilliform (a rash that looks like measles)

What are the common drug interactions of Lescol and Hydramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Compression fracture (fracture due to pressure caused by injury)
  3. Constipation
  4. Cough
  5. Depression
  6. Disability
  7. Dizziness
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Febrile neutropenia (fever with reduced white blood cells)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Discomfort
  4. Dry mouth
  5. Dysphonia (speech disorder attributable to a disorder of phonation)
  6. Emotional distress
  7. Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
  8. Fall
  9. Feeling jittery
  10. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 6 people, 35.29%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 11.76%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
  4. Nausea (feeling of having an urge to vomit): 1 person, 5.88%
  5. Metastases To Bone (cancer spreads to bone): 1 person, 5.88%
  6. Immunodeficiency Common Variable: 1 person, 5.88%
  7. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.88%
  8. Chest Pain: 1 person, 5.88%
  9. Cardiac Disorder: 1 person, 5.88%
  10. Back Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Lescol and Hydramine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lescol and Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lescol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lescol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydramine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluvastatin sodium and diphenhydramine hydrochloride (the active ingredients of Lescol and Hydramine, respectively), and Lescol and Hydramine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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