Letairis and Nitro-bid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Letairis (ambrisentan) and Nitro-bid (nitroglycerin). Common drug interactions include asthenia among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Letairis and Nitro-bid. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Letairis?

Letairis has active ingredients of ambrisentan. It is often used in pulmonary hypertension. eHealthMe is studying from 94,041 Letairis users. Check the latest studies of Letairis.

What is Nitro-bid?

Nitro-bid has active ingredients of nitroglycerin. eHealthMe is studying from 653 Nitro-bid users. Check the latest studies of Nitro-bid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

17 people who take Letairis and Nitro-bid together, and have interactions are studied.

Letairis and Nitro-bid drug interactions.

What are the common drug interactions of Letairis and Nitro-Bid, by gender? *:

female:

Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood urea increased
Brain natriuretic peptide increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Swelling
Renal failure (kidney dysfunction)

What are the common drug interactions of Letairis and Nitro-Bid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Acute respiratory failure
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood urea increased
Brain natriuretic peptide increased
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)

50-59:

Joint swelling
Viral infection
Epistaxis (bleed from the nose)
Headache (pain in head)

60+:

Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Swelling
Ankle fracture
Fall
Intra-abdominal haematoma (intra-abdominal localized swelling filled with blood)
Pneumonia
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 14 people, 82.35%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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