Letrozole and Effexor xr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Letrozole (letrozole) and Effexor xr (venlafaxine hydrochloride). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Letrozole and Effexor xr. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Letrozole?

Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.

What is Effexor xr?

Effexor xr has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 35,233 Effexor xr users. Check the latest studies of Effexor xr.

On Jul, 05, 2026

79 people who take Letrozole and Effexor xr together, and have interactions are studied.

Letrozole and Effexor xr drug interactions.

What are the common drug interactions of Letrozole and Effexor Xr, by gender? *:

female:

Arthralgia (joint pain)
Pain in extremity
Bone disorder
Eating disorder
Emotional distress
Exostosis (formation of new bone on the surface of a bone)
Gingival pain (gum pain)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)

male:

n/a

What are the common drug interactions of Letrozole and Effexor Xr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Bone pain
Dysphonia (speech disorder attributable to a disorder of phonation)
Epistaxis (bleed from the nose)
Swelling
Diarrhoea
Hot flush (sudden feelings of heat)

40-49:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Alopecia (absence of hair from areas of the body)
Constipation
Decreased appetite
Decreased interest
Diarrhoea
Dry skin
Full blood count decreased
Headache (pain in head)

50-59:

Osteonecrosis of jaw (death of bone of jaw)
Proctalgia (pain in the rectum)
Rectal abscess (pus in rectum)
Rectal fissure (painful condition in which a cut or tear occurs in the anus)
Cellulitis (infection under the skin)
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Purulent discharge (discharge that contains pus)
Seborrhoeic keratosis (noncancerous (benign) skin growths that some people develop as they age. they often appear on the back or chest)
Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

60+:

Alopecia (absence of hair from areas of the body)
White blood cell count decreased
Decreased appetite
Dementia (madness)
Disease progression
Disease recurrence
Drug dependence
Drug ineffective
Hepatic enzyme increased
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Breast Cancer Metastatic: 32 people, 40.51%
Breast Cancer Female: 30 people, 37.97%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 22 people, 27.85%
Pain: 6 people, 7.59%
Hot Flush (sudden feelings of heat): 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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