Letrozole and Efudex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Letrozole (letrozole) and Efudex (fluorouracil). Common drug interactions include malignant neoplasm progression among females.
The phase IV clinical study analyzes what interactions people have when they take Letrozole and Efudex. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Letrozole?
Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.
What is Efudex?
Efudex has active ingredients of fluorouracil. It is often used in actinic keratosis. eHealthMe is studying from 1,391 Efudex users. Check the latest studies of Efudex.
16 people who take Letrozole and Efudex together, and have interactions are studied.

What are the common drug interactions of Letrozole and Efudex, by gender? *:
female:
- Malignant neoplasm progression (cancer tumour came back)
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Depression
male:
n/a
What are the common drug interactions of Letrozole and Efudex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Breast mass
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
40-49:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
50-59:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Depression
60+:
n/a
What are the existing conditions these people have? *
- Breast Cancer Metastatic: 10 people, 62.50%
- Breast Cancer Female: 4 people, 25.00%
* Approximation only. Some reports may have incomplete information.
Do you take Letrozole and Efudex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Letrozole and Efudex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Letrozole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Efudex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Letrozole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Efudex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on letrozole and fluorouracil (the active ingredients of Letrozole and Efudex, respectively), and Letrozole and Efudex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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