Letrozole and Farxiga drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Letrozole (letrozole) and Farxiga (dapagliflozin). Common drug interactions include hereditary angioedema among females and white blood cell count decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Letrozole and Farxiga. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Letrozole?
Letrozole has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 54,125 Letrozole users. Check the latest studies of Letrozole.
What is Farxiga?
Farxiga has active ingredients of dapagliflozin. It is often used in diabetes. eHealthMe is studying from 18,798 Farxiga users. Check the latest studies of Farxiga.
28 people who take Letrozole and Farxiga together, and have interactions are studied.

What are the common drug interactions of Letrozole and Farxiga, by gender? *:
female:
- Hereditary angioedema (recurrent episodes of severe swelling)
- Blood glucose decreased
- Death
- Blood potassium increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Fall
- Upper respiratory tract infection
- Anger
- Asthenia (weakness)
- Axillary pain
male:
- White blood cell count decreased
What are the common drug interactions of Letrozole and Farxiga, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Hereditary angioedema (recurrent episodes of severe swelling)
- Stress
- Initial insomnia (feeling of inadequate or poor-quality sleep)
- Injection site pruritus (severe itching at injection site)
- Pain
- Depression
- Injection site erythema (redness at injection site)
- Injection site reaction
- Injection site swelling
- Memory impairment
60+:
- Weight decreased
- Diarrhoea
- Fall
- Upper respiratory tract infection
- Anger
- Asthenia (weakness)
- Axillary pain
- Burning sensation
- Chills (felling of cold)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
What are the existing conditions these people have? *
- High Blood Cholesterol: 7 people, 25.00%
- Neuropathy Peripheral (surface nerve damage): 5 people, 17.86%
- High Blood Pressure: 5 people, 17.86%
- Type 2 Diabetes: 5 people, 17.86%
- Neoplasm Malignant (cancer tumour): 4 people, 14.29%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 10.71%
- Breast Cancer Female: 3 people, 10.71%
- Breast Cancer Metastatic: 3 people, 10.71%
- Hereditary Angioedema (recurrent episodes of severe swelling): 3 people, 10.71%
- Osteoporosis (bones weak and more likely to break): 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Letrozole and Farxiga?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Letrozole and Farxiga:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Letrozole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Farxiga:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Letrozole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Farxiga and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on letrozole and dapagliflozin (the active ingredients of Letrozole and Farxiga, respectively), and Letrozole and Farxiga (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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