Leukine and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leukine (sargramostim) and Actonel (risedronate sodium). Common drug interactions include erythema among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Leukine and Actonel. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

On Jul, 08, 2026

26 people who take Leukine and Actonel together, and have interactions are studied.

What are the common drug interactions of Leukine and Actonel, by gender? *:

female:

Erythema (redness of the skin)
Anaemia (lack of blood)
Breast cancer female
Intervertebral disc protrusion (spinal disc protrusion)
Ovarian cyst (fluid filled sac of the ovary)
Abdominal pain
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Abdominal pain
Alveolar aeration excessive
Atrophic vulvovaginitis (inflammation of the vulva)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone disorder
Bone pain
Breathing-related sleep disorder
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cellulitis (infection under the skin)

What are the common drug interactions of Leukine and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Exostosis (formation of new bone on the surface of a bone)
Hepatic lesion
Hypersensitivity
Irritability
Joint sprain (an injury to joint surrounding flexible fibres)
Joint stiffness
Menopause (end of monthly cycles in women)
Mood swings (an extreme or rapid change in mood)
Pain

40-49:

n/a

50-59:

Back pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation
Depression
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dysthymic disorder (mild chronic depression disorder)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Epistaxis (bleed from the nose)
Fall

60+:

Dyspnoea (difficult or laboured respiration)
Hospitalisation
Hypoxia (low oxygen in tissues)
Pneumonia
Pulmonary toxicity (side effects on the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Vitiligo (pigment is lost from areas of the skin): 12 people, 46.15%
Lung Cancer - Non-Small Cell (lung cancer): 12 people, 46.15%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 12 people, 46.15%
Pain: 5 people, 19.23%

* Approximation only. Some reports may have incomplete information.

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