Leukine and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leukine (sargramostim) and Aredia (pamidronate disodium). Common drug interactions include hypertension among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Leukine and Aredia. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.

On Jul, 29, 2026

49 people who take Leukine and Aredia together, and have interactions are studied.

What are the common drug interactions of Leukine and Aredia, by gender? *:

female:

Hypertension (high blood pressure)
Anxiety
Death
Dysarthria (speech disorder)
Lymphadenopathy (disease or enlargement of lymph nodes)
Toothache (tooth pain)
Depression
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)

male:

Pain
Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Nephrolithiasis (calculi in the kidneys)
Weight decreased
Toothache (tooth pain)
Neutropenia (an abnormally low number of neutrophils)
Bone disorder
Renal cyst (kidney cyst)
Spinal osteoarthritis (joint cartilage loss in spine)

What are the common drug interactions of Leukine and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal distension
Abdominal pain upper
Abscess jaw (tooth abscess or root abscess)
Actinomycosis (infection that causes sores, or abscesses)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia of chronic disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

20-29:

n/a

30-39:

Accident
Affective disorder (mental disorder)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Anxiety
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve incompetence
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

40-49:

Dysarthria (speech disorder)
Hypertension (high blood pressure)
Pain
Abdominal discomfort
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)

50-59:

Anaemia (lack of blood)

60+:

Pain
Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Nephrolithiasis (calculi in the kidneys)
Weight decreased
Toothache (tooth pain)
Anxiety
Bone disorder
Neutropenia (an abnormally low number of neutrophils)
Hyperlipidaemia (presence of excess lipids in the blood)

What are the existing conditions these people have? *

Prostate Cancer: 13 people, 26.53%
Osteoporosis (bones weak and more likely to break): 13 people, 26.53%
High Blood Cholesterol: 11 people, 22.45%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 7 people, 14.29%
Gynecomastia (enlargement of the gland tissue of the male breast): 7 people, 14.29%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 10.20%

* Approximation only. Some reports may have incomplete information.

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