Leukine and Coumadin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Leukine (sargramostim) and Coumadin (warfarin sodium). Common drug interactions include anxiety among females and pulmonary embolism among males.
The phase IV clinical study analyzes what interactions people have when they take Leukine and Coumadin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.
What is Leukine?
Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.
What is Coumadin?
Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.
77 people who take Leukine and Coumadin together, and have interactions are studied.

What are the common drug interactions of Leukine and Coumadin, by gender? *:
female:
- Anxiety
- Pyrexia (fever)
- Erythema (redness of the skin)
- Hypertension (high blood pressure)
- Osteomyelitis (infection of bone)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Appetite disorder (abnormal eating habits)
- Back pain
- Bone disorder
male:
- Pulmonary embolism (blockage of the main artery of the lung)
- Thrombocytopenia (decrease of platelets in blood)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Aphasia (damage to the parts of the brain that control language)
- Back pain
- Disability
- Hypertension (high blood pressure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Injury
What are the common drug interactions of Leukine and Coumadin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Brain abscess
- Drug maladministration
- Flushing (the warm, red condition of human skin)
- Injection site bruising
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Thrombosis (formation of a blood clot inside a blood vessel)
40-49:
- Nausea (feeling of having an urge to vomit)
- Pain
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Anticoagulation drug level above therapeutic
- Arthralgia (joint pain)
- Chest pain
- Diarrhoea
- Dysarthria (speech disorder)
- Febrile neutropenia (fever with reduced white blood cells)
- Hypertension (high blood pressure)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Appetite disorder (abnormal eating habits)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Back pain
- Chills (felling of cold)
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Constipation
- Depression
- Dizziness
60+:
- Pulmonary embolism (blockage of the main artery of the lung)
- Anxiety
- Urinary hesitation (difficulty in beginning the flow of urine)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Pleural effusion (water on the lungs)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Aphasia (damage to the parts of the brain that control language)
- Cellulitis (infection under the skin)
- Loss of consciousness
What are the existing conditions these people have? *
- Malignant Melanoma (skin cancer rises from melancytes): 12 people, 15.58%
- Lung Cancer - Non-Small Cell (lung cancer): 10 people, 12.99%
- Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 10 people, 12.99%
- Pain: 5 people, 6.49%
- Prostate Cancer: 4 people, 5.19%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 5.19%
* Approximation only. Some reports may have incomplete information.
Do you take Leukine and Coumadin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Leukine and Coumadin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Leukine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Coumadin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Leukine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coumadin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sargramostim and warfarin sodium (the active ingredients of Leukine and Coumadin, respectively), and Leukine and Coumadin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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