Levemir and Vicodin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levemir (insulin detemir recombinant) and Vicodin (acetaminophen; hydrocodone bitartrate). Common drug interactions include renal impairment among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Levemir and Vicodin. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Levemir?

Levemir has active ingredients of insulin detemir recombinant. It is often used in diabetes. eHealthMe is studying from 13,850 Levemir users. Check the latest studies of Levemir.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

On Aug, 09, 2026

79 people who take Levemir and Vicodin together, and have interactions are studied.

What are the common drug interactions of Levemir and Vicodin, by gender? *:

female:

Renal impairment (severely reduced kidney function)
Abdominal pain
Bile duct stone
Blood glucose increased
Diarrhoea
Renal failure (kidney dysfunction)
Spinal fracture (fracture in one of vertebrae)
Asthenia (weakness)
Ataxia (loss of full control of bodily movements)
Bone pain

male:

Blood glucose increased
Dizziness
Diastolic dysfunction
Dysarthria (speech disorder)
Dysphonia (speech disorder attributable to a disorder of phonation)
Erectile dysfunction
Gastritis (inflammation of stomach)
Injury
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)

What are the common drug interactions of Levemir and Vicodin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal discomfort
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Bile duct stone
Chest discomfort
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Renal injury (kidney injury)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Urticaria (rash of round, red welts on the skin that itch intensely)

30-39:

n/a

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Aortic valve disease
Arthralgia (joint pain)
Asthma
Balance disorder
Blood glucose increased
Blood pressure diastolic increased
Blood pressure systolic decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Burning sensation

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood disorder
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Erectile dysfunction
Eye swelling
Fall
Flushing (the warm, red condition of human skin)
Gallbladder disorder
Large intestine perforation (hole in large intestine)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Urinary tract infection
Abdominal discomfort
Blood glucose increased
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Renal impairment (severely reduced kidney function)
Anxiety
Diarrhoea
Dizziness

What are the existing conditions these people have? *

Type 2 Diabetes: 11 people, 13.92%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 10 people, 12.66%
High Blood Pressure: 9 people, 11.39%

* Approximation only. Some reports may have incomplete information.

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