Levetiracetam and Gleevec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levetiracetam (levetiracetam) and Gleevec (imatinib mesylate). Common drug interactions include death among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Levetiracetam and Gleevec. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Levetiracetam?

Levetiracetam has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 75,292 Levetiracetam users. Check the latest studies of Levetiracetam.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.



On Aug, 08, 2026

16 people who take Levetiracetam and Gleevec together, and have interactions are studied.

Levetiracetam and Gleevec drug interactions.

What are the common drug interactions of Levetiracetam and Gleevec, by gender? *:

female:

  1. Death
  2. Cardiac disorder
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Dyspnoea (difficult or laboured respiration)
  5. Encephalomalacia (localized softening of the brain substance, due to haemorrhage or inflammation)
  6. Insomnia (sleeplessness)
  7. Lactic acidosis (low ph in body tissues)
  8. Liver disorder (liver diseases)
  9. Neoplasm (tumour)
  10. Pericardial effusion (fluid around the heart)

male:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Death
  3. Muscle spasms (muscle contraction)
  4. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  5. Neoplasm malignant (cancer tumour)
  6. Neoplasm progression (growth of tumour)
  7. Pain in extremity
  8. Pyrexia (fever)
  9. Vomiting
  10. Anaemia (lack of blood)

What are the common drug interactions of Levetiracetam and Gleevec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Death

50-59:

  1. Glossodynia (a burning or painful sensation in the tongue)
  2. Leukopenia (less number of white blood cells in blood)
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Anaemia (lack of blood)
  6. Dysgeusia (disorder of the sense of taste)

60+:

  1. Death
  2. Drug ineffective
  3. Dyspnoea (difficult or laboured respiration)
  4. Lactic acidosis (low ph in body tissues)
  5. Leukaemia recurrent (repeat cancer of bone marrow or blood cells)
  6. Pleural effusion (water on the lungs)
  7. Renal failure acute (rapid kidney dysfunction)
  8. White blood cell count decreased

What are the existing conditions these people have? *

  1. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 18.75%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 12.50%
  3. Spindle Cell Sarcoma (a type of connective tissue cancer in which the cells): 1 person, 6.25%
  4. Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
  5. High Blood Pressure: 1 person, 6.25%
  6. Hemiplegia (paralysis of one side of the body): 1 person, 6.25%
  7. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 1 person, 6.25%
  8. Gastrointestinal Stromal Tumor: 1 person, 6.25%
  9. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Levetiracetam and Gleevec?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levetiracetam and Gleevec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levetiracetam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gleevec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levetiracetam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gleevec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levetiracetam and imatinib mesylate (the active ingredients of Levetiracetam and Gleevec, respectively), and Levetiracetam and Gleevec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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