Levocarnitine and Methotrexate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levocarnitine (levocarnitine) and Methotrexate sodium (methotrexate sodium). Common drug interactions include bacteraemia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Levocarnitine and Methotrexate sodium. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Levocarnitine?

Levocarnitine has active ingredients of levocarnitine. It is often used in mitochondrial myopathy. eHealthMe is studying from 3,332 Levocarnitine users. Check the latest studies of Levocarnitine.

What is Methotrexate sodium?

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,679 Methotrexate sodium users. Check the latest studies of Methotrexate sodium.



On Jul, 20, 2026

17 people who take Levocarnitine and Methotrexate sodium together, and have interactions are studied.

Levocarnitine and Methotrexate sodium drug interactions.

What are the common drug interactions of Levocarnitine and Methotrexate Sodium, by gender? *:

female:

  1. Bacteraemia (presence of bacteria in the blood)

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Cellulitis (infection under the skin)
  3. Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
  4. Headache (pain in head)
  5. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  6. Hepatic failure (liver failure)
  7. Liver disorder (liver diseases)
  8. Nausea (feeling of having an urge to vomit)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Oedema peripheral (superficial swelling)

What are the common drug interactions of Levocarnitine and Methotrexate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Febrile neutropenia (fever with reduced white blood cells)

10-19:

  1. Decreased appetite
  2. Diarrhoea
  3. Enterocolitis infectious
  4. Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
  5. Headache (pain in head)
  6. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  7. Hepatic failure (liver failure)
  8. Liver disorder (liver diseases)
  9. Nausea (feeling of having an urge to vomit)
  10. Neutropenia (an abnormally low number of neutrophils)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Diarrhoea
  2. Renal injury (kidney injury)

60+:

n/a

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 15 people, 88.24%
  2. Blood Pressure Abnormal: 2 people, 11.76%
  3. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 5.88%
  4. Neuropathy Peripheral (surface nerve damage): 1 person, 5.88%
  5. Hypertriglyceridaemia (excess of triglycerides in the blood): 1 person, 5.88%
  6. Gastric Ph Decreased: 1 person, 5.88%
  7. Bacterial Infection: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Levocarnitine and Methotrexate sodium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levocarnitine and Methotrexate sodium:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levocarnitine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methotrexate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levocarnitine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methotrexate sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levocarnitine and methotrexate sodium (the active ingredients of Levocarnitine and Methotrexate sodium, respectively), and Levocarnitine and Methotrexate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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