Levocarnitine and Provigil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Levocarnitine (levocarnitine) and Provigil (modafinil). Common drug interactions include dizziness among females and hypertension among males.
The phase IV clinical study analyzes what interactions people have when they take Levocarnitine and Provigil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Levocarnitine?
Levocarnitine has active ingredients of levocarnitine. It is often used in mitochondrial myopathy. eHealthMe is studying from 3,332 Levocarnitine users. Check the latest studies of Levocarnitine.
What is Provigil?
Provigil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 25,230 Provigil users. Check the latest studies of Provigil.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
18 people who take Levocarnitine and Provigil together, and have interactions are studied.

What are the common drug interactions of Levocarnitine and Provigil, by gender? *:
female:
- Dizziness
- Muscular weakness (muscle weakness)
- Myalgia (muscle pain)
- Alopecia (absence of hair from areas of the body)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Constipation
- Diarrhoea
- Herpes simplex (herpes simplex is a common viral infection)
- Injection site discolouration
male:
- Hypertension (high blood pressure)
- Renal disorder (kidney disease)
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
- Renal impairment (severely reduced kidney function)
- Blood glucose decreased
- Blood pressure decreased
- Contusion (a type of hematoma of tissue in which capillaries)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Drug hypersensitivity
What are the common drug interactions of Levocarnitine and Provigil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Hypoxia (low oxygen in tissues)
- Pleural effusion (water on the lungs)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pulmonary embolism (blockage of the main artery of the lung)
- Pulmonary infarction (death of a small area of lung)
30-39:
- Abdominal discomfort
- Feeling drunk
- Nausea (feeling of having an urge to vomit)
40-49:
n/a
50-59:
n/a
60+:
- Dizziness
- Alopecia (absence of hair from areas of the body)
- Muscle disorder (muscle disease)
- Muscular weakness (muscle weakness)
- Myalgia (muscle pain)
- Neck pain
- Peroneal nerve palsy
- Thyroid disorder (thyroid diseases)
- Trichorrhexis (a condition in which the hairs break)
- Visual impairment
What are the existing conditions these people have? *
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 38.89%
- Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 4 people, 22.22%
- Myositis (inflammation of the muscles): 4 people, 22.22%
- Muscle Aches (muscle pain): 4 people, 22.22%
- Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 4 people, 22.22%
- Connective Tissue Disorder (any disease that has the connective tissues of the body): 4 people, 22.22%
- Sleep Disorder: 2 people, 11.11%
- Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 11.11%
- Hiv Infection: 2 people, 11.11%
- Drowsiness: 2 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Levocarnitine and Provigil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Levocarnitine (3,332 reports)
- Provigil (25,230 reports)
Browse all drug interactions of Levocarnitine and Provigil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Levocarnitine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Provigil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levocarnitine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Provigil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on levocarnitine and modafinil (the active ingredients of Levocarnitine and Provigil, respectively), and Levocarnitine and Provigil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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