Levocetirizine dihydrochloride and Excedrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levocetirizine dihydrochloride (levocetirizine dihydrochloride) and Excedrin (acetaminophen; aspirin; caffeine). Common drug interactions include asthma among females.

The phase IV clinical study analyzes what interactions people have when they take Levocetirizine dihydrochloride and Excedrin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Levocetirizine dihydrochloride?

Levocetirizine dihydrochloride has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 3,258 Levocetirizine dihydrochloride users. Check the latest studies of Levocetirizine dihydrochloride.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.



On Aug, 11, 2026

11 people who take Levocetirizine dihydrochloride and Excedrin together, and have interactions are studied.

Levocetirizine dihydrochloride and Excedrin drug interactions.

What are the common drug interactions of Levocetirizine Dihydrochloride and Excedrin, by gender? *:

female:

  1. Asthma
  2. Chest discomfort
  3. Swollen tongue (swelling of tongue)
  4. Throat tightness
  5. Tongue disorder (disease of tongue)
  6. Upper respiratory tract infection
  7. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  8. Blood calcium increased
  9. Cardiac disorder
  10. Chest pain

male:

n/a

What are the common drug interactions of Levocetirizine Dihydrochloride and Excedrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pruritus generalised (generalized itching)
  2. Urinary retention (the inability to completely or partially empty the bladder)

40-49:

n/a

50-59:

  1. Asthma
  2. Chest discomfort
  3. Dyspnoea (difficult or laboured respiration)
  4. Fall
  5. Infusion related reaction
  6. Ligament rupture (tear in ligament)
  7. Ligament sprain (ligament stretched)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Oral herpes (viral infection of mouth)
  10. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)

60+:

  1. Blood calcium increased
  2. Cardiac disorder
  3. Injection site pain
  4. Nausea (feeling of having an urge to vomit)
  5. Pruritus (severe itching of the skin)
  6. Vitamin d decreased
  7. Vomiting
  8. Abdominal pain upper
  9. Constipation
  10. Dizziness

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 5 people, 45.45%
  2. Osteoporosis (bones weak and more likely to break): 2 people, 18.18%
  3. Migraine (headache): 2 people, 18.18%
  4. Inner Ear Disorder: 2 people, 18.18%
  5. Depression: 2 people, 18.18%
  6. Senile Osteoporosis (weak bones with ageing): 1 person, 9.09%
  7. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 1 person, 9.09%
  8. Hypersensitivity: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Levocetirizine dihydrochloride and Excedrin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levocetirizine dihydrochloride and Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levocetirizine dihydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levocetirizine dihydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Excedrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levocetirizine dihydrochloride and acetaminophen; aspirin; caffeine (the active ingredients of Levocetirizine dihydrochloride and Excedrin, respectively), and Levocetirizine dihydrochloride and Excedrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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