Levofloxacin and Clolar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levofloxacin (levofloxacin; sodium chloride) and Clolar (clofarabine). Common drug interactions include retrograde portal vein flow among females and aspartate aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Levofloxacin and Clolar. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Levofloxacin?

Levofloxacin has active ingredients of levofloxacin; sodium chloride. It is often used in sinusitis. eHealthMe is studying from 16,335 Levofloxacin users. Check the latest studies of Levofloxacin.

What is Clolar?

Clolar has active ingredients of clofarabine. eHealthMe is studying from 1,093 Clolar users. Check the latest studies of Clolar.

On Jul, 13, 2026

21 people who take Levofloxacin and Clolar together, and have interactions are studied.

Levofloxacin and Clolar drug interactions.

What are the common drug interactions of Levofloxacin and Clolar, by gender? *:

female:

Retrograde portal vein flow
Splenic infection (infection to spleen)
Splenic lesion (lesion on spleen)
Splenomegaly (enlargement of spleen)
Staphylococcal infection (an infection with staphylococcus bacteria)
Stem cell transplant
Venoocclusive liver disease (small veins in the liver are obstructed)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Disease progression

male:

Aspartate aminotransferase increased
Blood creatinine increased
Blood bilirubin increased
Blood amylase increased
Cardiomyopathy (weakening of the heart muscle)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Coagulopathy (blood's ability to clot is impaired)
Fungal infection
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypokalaemia (low potassium)

What are the common drug interactions of Levofloxacin and Clolar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Transaminases increased
Venoocclusive liver disease (small veins in the liver are obstructed)
White blood cell count decreased
White blood cell disorder
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Alanine aminotransferase increased
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Gastrointestinal infection (infection of stomach and intestine)
Hypercoagulation (increased tendency for clotting of the blood)

20-29:

Renal failure acute (rapid kidney dysfunction)
Abdominal pain
Anuria (failure of the kidneys to produce urine)
Ascites (accumulation of fluid in the abdominal cavity)
Blood bilirubin increased
Blood culture positive
Collapse of lung (functional breakdown of lung)
Decreased appetite
Electrocardiogram qt prolonged
Febrile neutropenia (fever with reduced white blood cells)

30-39:

n/a

40-49:

Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bk virus infection
Blood bilirubin increased
Diarrhoea
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)

50-59:

Graft versus host disease in intestine (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body and damages intestinal mucosal membrane)
Proctalgia (pain in the rectum)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Culture stool positive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Enterococcal infection
Febrile neutropenia (fever with reduced white blood cells)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 15 people, 71.43%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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