1. Home
  2. Analysis
  3. Levonorgestrel
  4. Progesterone

Levonorgestrel and Progesterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levonorgestrel (levonorgestrel) and Progesterone (progesterone). Common drug interactions include pelvic pain among females.

The phase IV clinical study analyzes what interactions people have when they take Levonorgestrel and Progesterone. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Levonorgestrel?

Levonorgestrel has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 4,186 Levonorgestrel users. Check the latest studies of Levonorgestrel.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

On Jul, 10, 2026

12 people who take Levonorgestrel and Progesterone together, and have interactions are studied.

Levonorgestrel and Progesterone drug interactions.

What are the common drug interactions of Levonorgestrel and Progesterone, by gender? *:

female:

  1. Pelvic pain
  2. Genital haemorrhage (bleeding from genital)
  3. Breast pain
  4. Crying
  5. Drug ineffective
  6. Dysmenorrhoea (painful menstruation)
  7. Dyspareunia (painful sexual intercourse)
  8. Eyelids pruritus (eyelids itching)
  9. Fatigue (feeling of tiredness)
  10. Female sexual dysfunction (change in sexual function)

male:

n/a

What are the common drug interactions of Levonorgestrel and Progesterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Genital haemorrhage (bleeding from genital)
  2. Pelvic pain
  3. Drug ineffective

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal pain lower
  2. Abdominal pain upper
  3. Dyspareunia (painful sexual intercourse)
  4. Eyelids pruritus (eyelids itching)
  5. Fatigue (feeling of tiredness)
  6. Female sexual dysfunction (change in sexual function)
  7. Hot flush (sudden feelings of heat)
  8. Hypersensitivity
  9. Hypertriglyceridaemia (excess of triglycerides in the blood)
  10. Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Dysmenorrhea (painful menstruation): 5 people, 41.67%
  2. Premature Menopause: 2 people, 16.67%
  3. Ovarian Failure (ovary is not functioning): 2 people, 16.67%
  4. Visual Impairment: 1 person, 8.33%
  5. Pain: 1 person, 8.33%
  6. Headache (pain in head): 1 person, 8.33%
  7. Asthma: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Levonorgestrel and Progesterone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levonorgestrel and Progesterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levonorgestrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Progesterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levonorgestrel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Progesterone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel and progesterone (the active ingredients of Levonorgestrel and Progesterone, respectively), and Levonorgestrel and Progesterone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.