Levophed and Bumetanide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levophed (norepinephrine bitartrate) and Bumetanide (bumetanide). Common drug interactions include acne among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Levophed and Bumetanide. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Levophed?

Levophed has active ingredients of norepinephrine bitartrate. eHealthMe is studying from 2,047 Levophed users. Check the latest studies of Levophed.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.



On Jul, 27, 2026

15 people who take Levophed and Bumetanide together, and have interactions are studied.

Levophed and Bumetanide drug interactions.

What are the common drug interactions of Levophed and Bumetanide, by gender? *:

female:

  1. Acne (skin problems that cause pimples)
  2. Alanine aminotransferase increased
  3. Anaemia (lack of blood)
  4. Angiopathy (generic term for a disease of the blood vessels)
  5. Aspartate aminotransferase increased
  6. Cardiac failure congestive
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cholecystitis (infection of gallbladder)
  9. Influenza like illness
  10. Insomnia (sleeplessness)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Acidosis (build-up of carbon dioxide in the blood)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Alanine aminotransferase increased
  5. Aspartate aminotransferase increased
  6. Blood creatinine increased
  7. Delirium (wild excitement)
  8. Hypokalaemia (low potassium)
  9. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  10. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)

What are the common drug interactions of Levophed and Bumetanide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Acute myocardial infarction (acute heart attack)
  2. Arteriosclerosis (thickening and hardening of arteries)
  3. Asthenia (weakness)
  4. Bladder disorder
  5. Blood potassium decreased
  6. Blood potassium increased
  7. Chest pain
  8. Eclampsia (acute and life-threatening complication of pregnancy)
  9. Electrocardiogram qt prolonged
  10. Electrocardiogram repolarisation abnormality

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Abdominal pain
  3. Acne (skin problems that cause pimples)
  4. Alanine aminotransferase increased
  5. Aspartate aminotransferase increased
  6. Dysuria (painful or difficult urination)
  7. Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
  8. Pyrexia (fever)
  9. Vomiting
  10. Vulval abscess

40-49:

  1. Cerebral infarction (less blood supply to brain resulting tissue damage)
  2. Dyspnoea (difficult or laboured respiration)
  3. Injury
  4. Pain
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Thrombotic stroke (stroke due to clot formation)

50-59:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Blood creatinine increased

60+:

  1. Hypotension (abnormally low blood pressure)
  2. Acidosis (build-up of carbon dioxide in the blood)
  3. Renal failure (kidney dysfunction)
  4. Renal tubular necrosis (death of kidney tubules)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Cardiac failure congestive
  7. Death
  8. Delirium (wild excitement)
  9. Hypokalaemia (low potassium)
  10. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

What are the existing conditions these people have? *

  1. Agitation (state of anxiety or nervous excitement): 2 people, 13.33%
  2. Peripartum Cardiomyopathy (deterioration in cardiac function presenting typically between the last month of pregnancy and up to five months postpartum): 2 people, 13.33%
  3. Birth Control: 2 people, 13.33%
  4. Urination - Excessive Volume: 1 person, 6.67%
  5. Fever: 1 person, 6.67%
  6. Acne (skin problems that cause pimples): 1 person, 6.67%
  7. Acute Bronchitis (acute inflammation of the large bronchi (medium-size airways) in the lungs): 1 person, 6.67%
  8. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 6.67%
  9. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 1 person, 6.67%
  10. Bacterial Infection: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Levophed and Bumetanide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levophed and Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levophed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levophed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumetanide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on norepinephrine bitartrate and bumetanide (the active ingredients of Levophed and Bumetanide, respectively), and Levophed and Bumetanide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: