Levophed and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levophed (norepinephrine bitartrate) and Midazolam (midazolam). Common drug interactions include aspartate aminotransferase increased among females and septic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Levophed and Midazolam. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Levophed?

Levophed has active ingredients of norepinephrine bitartrate. eHealthMe is studying from 2,047 Levophed users. Check the latest studies of Levophed.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

On Jul, 21, 2026

42 people who take Levophed and Midazolam together, and have interactions are studied.

Levophed and Midazolam drug interactions.

What are the common drug interactions of Levophed and Midazolam, by gender? *:

female:

Aspartate aminotransferase increased
Alanine aminotransferase increased
Cardiac arrest
Disease complication
Hepatic steatosis (fatty liver disease)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Lymphadenopathy (disease or enlargement of lymph nodes)
Platelet count decreased

male:

Septic shock (shock due to blood infection)
Alanine aminotransferase increased
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Urinary tract infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Acute respiratory distress syndrome
Blood alkaline phosphatase increased
Blood creatinine increased
Respiratory failure (inadequate gas exchange by the respiratory system)
Acute hepatic failure

What are the common drug interactions of Levophed and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aspartate aminotransferase increased
Blood calcium decreased
Blood creatinine increased
Blood urea increased
Cardiogenic shock (inadequate circulation of blood)
Haematocrit decreased
Septic shock (shock due to blood infection)
White blood cell count increased
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased

30-39:

Alanine aminotransferase increased
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)

40-49:

Alanine aminotransferase increased
Abdominal sepsis (abdominal infection)
Blood alkaline phosphatase increased
Gastric ulcer perforation (stomach hole due to ulcer)
Hepatitis (inflammation of the liver)
Myocarditis (inflammation of heart muscle myocardium)

50-59:

Septic shock (shock due to blood infection)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Malignant neoplasm of renal pelvis (cancer tumour of ureter)
Melaena (the passage of black, tarry stools)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Pneumonia
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Urinary tract infection
Hypokalaemia (low potassium)
Acute hepatic failure

60+:

Haemorrhage (bleeding)
Alanine aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood alkaline phosphatase increased
Blood bilirubin increased
Blood fibrinogen decreased
Bradycardia (abnormally slow heart action)
Death
Hepatic failure (liver failure)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 10 people, 23.81%
Sedation: 6 people, 14.29%
Pneumonia: 6 people, 14.29%
Hypotension (abnormally low blood pressure): 6 people, 14.29%
Fever: 6 people, 14.29%
Pain: 4 people, 9.52%
Type 2 Diabetes: 3 people, 7.14%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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