Levothroid and Asa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Asa (aspirin). Common drug interactions include gastrooesophageal reflux disease among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Levothroid and Asa. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

On Jul, 18, 2026

48 people who take Levothroid and Asa together, and have interactions are studied.

What are the common drug interactions of Levothroid and Asa, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematochezia (passage of stools containing blood)
Hair colour changes
Hearing impaired
Hepatic lesion
Joint swelling
Knee arthroplasty
Local swelling (swelling at the site of some application of substance or injury)
Lymphoedema (localized fluid retention and tissue swelling)
Magnesium deficiency (lack of magnesium)

male:

Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Corneal disorder
Fall
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Memory impairment

What are the common drug interactions of Levothroid and Asa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Micturition urgency (urgency to pass the urine)
Oedema peripheral (superficial swelling)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back injury
Back pain
Blood pressure decreased
Hair colour changes

60+:

Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Akinesia (loss of control of voluntary muscle movements)
Anxiety
Gait disturbance
Hypokinesia (decreased bodily movement)
Amyloidosis (a tumour within which amyloid is produced)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 12.50%
Sleep Disorder: 5 people, 10.42%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 10.42%
Type 2 Diabetes: 4 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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