Levothroid and Clotrimazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Clotrimazole (clotrimazole). Common drug interactions include herpes zoster among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Levothroid and Clotrimazole. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Clotrimazole?

Clotrimazole has active ingredients of clotrimazole. It is often used in thrush. eHealthMe is studying from 13,947 Clotrimazole users. Check the latest studies of Clotrimazole.

On Jul, 19, 2026

27 people who take Levothroid and Clotrimazole together, and have interactions are studied.

Levothroid and Clotrimazole drug interactions.

What are the common drug interactions of Levothroid and Clotrimazole, by gender? *:

female:

Herpes zoster
Hip fracture
Humerus fracture (injury to the upper arm bone)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hyperkalaemia (damage to or disease of the kidney)
Hyperthyroidism (over activity of the thyroid gland)
Hypotension (abnormally low blood pressure)
Impaired fasting glucose
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Insomnia (sleeplessness)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Oxygen saturation decreased
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Grip strength decreased
Hair colour changes
Hyperkalaemia (damage to or disease of the kidney)
Hyperkeratosis (thickening of the outer layer of the skin)
Hypertension (high blood pressure)

What are the common drug interactions of Levothroid and Clotrimazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Human papilloma virus test positive
Lymphocyte count increased
Monocyte count increased
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Red blood cell count decreased
Red cell distribution width increased
Serum ferritin increased
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
White blood cell count increased
Transferrin saturation decreased

40-49:

Anxiety
Ascites (accumulation of fluid in the abdominal cavity)
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Escherichia sepsis (bacterial infection by escherichia coli)
Pain
Pleural effusion (water on the lungs)
Pyelonephritis (inflammation of kidney caused by bacteria)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

50-59:

Anogenital warts
Menopausal symptoms
Abdominal hernia
Anal cancer
Anorectal disorder
Anxiety
Body tinea (ringworm of the body)
Breast disorder
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Contusion (a type of hematoma of tissue in which capillaries)

60+:

Cardiac arrest
Chronic kidney disease
Blood pressure increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased appetite
Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Disease progression
Dysgeusia (disorder of the sense of taste)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 22.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 18.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 14.81%
High Blood Cholesterol: 4 people, 14.81%
Thyroid Diseases: 3 people, 11.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.11%
Swelling: 2 people, 7.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.41%
Pain: 2 people, 7.41%
Nausea (feeling of having an urge to vomit): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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