Levothroid and Esomeprazole magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Esomeprazole magnesium (esomeprazole magnesium). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Levothroid and Esomeprazole magnesium. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Esomeprazole magnesium?

Esomeprazole magnesium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 21,214 Esomeprazole magnesium users. Check the latest studies of Esomeprazole magnesium.

On Jul, 21, 2026

14 people who take Levothroid and Esomeprazole magnesium together, and have interactions are studied.

Levothroid and Esomeprazole magnesium drug interactions.

What are the common drug interactions of Levothroid and Esomeprazole Magnesium, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Muscle spasms (muscle contraction)
Pain
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic respiratory failure
Fibromyalgia (a long-term condition which causes pain all over the body)
Hypotension (abnormally low blood pressure)
Intervertebral disc degeneration (spinal disc degeneration)

male:

n/a

What are the common drug interactions of Levothroid and Esomeprazole Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic respiratory failure
Hypotension (abnormally low blood pressure)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Platelet count decreased
Procedural hypotension
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 42.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 14.29%
Pain: 2 people, 14.29%
Chronic Renal Failure (kidney failure): 2 people, 14.29%
Fluid Overload (too much fluid in the blood): 2 people, 14.29%
Vitamin D Decreased: 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%
Depression: 1 person, 7.14%
Diabetes: 1 person, 7.14%
Heart Rate Increased: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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