Levothroid and Prochlorperazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Prochlorperazine (prochlorperazine). Common drug interactions include abdominal pain upper among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Levothroid and Prochlorperazine. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Prochlorperazine?

Prochlorperazine has active ingredients of prochlorperazine. It is often used in nausea. eHealthMe is studying from 14,632 Prochlorperazine users. Check the latest studies of Prochlorperazine.



On Aug, 11, 2026

35 people who take Levothroid and Prochlorperazine together, and have interactions are studied.

Levothroid and Prochlorperazine drug interactions.

What are the common drug interactions of Levothroid and Prochlorperazine, by gender? *:

female:

  1. Abdominal pain upper
  2. Anxiety
  3. Asthenia (weakness)
  4. Burning sensation
  5. Cough
  6. Crying
  7. Dyspnoea exertional (breathlessness or shortness of breath)
  8. Headache (pain in head)
  9. Muscle spasms (muscle contraction)
  10. Pyrexia (fever)

male:

  1. Asthenia (weakness)
  2. Fatigue (feeling of tiredness)
  3. Aphonia (inability to produce voice)
  4. Arrhythmia (irregular heartbeat)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Asthma
  7. Attention deficit/hyperactivity disorder
  8. Autonomic failure syndrome (a degenerative disease of the autonomic nervous system)
  9. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  10. Blood glucose fluctuation

What are the common drug interactions of Levothroid and Prochlorperazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  2. Aphasia (damage to the parts of the brain that control language)
  3. Balance disorder
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Memory impairment
  6. Reading disorder (problem in areas of the brain that help interpret language)
  7. Activities of daily living impaired
  8. Anaplastic large cell lymphoma t- and null-cell types (t-cell or null-cell cancer, a type of blood cancer)
  9. Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
  10. Haemorrhage (bleeding)

40-49:

  1. Increased appetite
  2. Memory impairment
  3. Muscle spasms (muscle contraction)
  4. Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Vision blurred
  8. Alopecia (absence of hair from areas of the body)
  9. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  10. Drug ineffective

50-59:

  1. Hepatic neoplasm malignant (liver cancer)
  2. Rash

60+:

  1. Fatigue (feeling of tiredness)
  2. Asthenia (weakness)
  3. Fall
  4. Memory impairment
  5. Muscle atrophy (a decrease in the mass of the muscle)
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
  8. Photophobia (extreme sensitivity to light)
  9. Retching (strong involuntary effort to vomit)
  10. Tearfulness (excess tearing)

What are the existing conditions these people have? *

  1. Pain: 5 people, 14.29%
  2. Hepatitis C: 4 people, 11.43%
  3. Rectal Cancer (cancer of rectum): 3 people, 8.57%
  4. Muscle Spasms (muscle contraction): 3 people, 8.57%
  5. Multiple Myeloma (cancer of the plasma cells): 3 people, 8.57%
  6. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 5.71%
  7. Thyroid Diseases: 2 people, 5.71%
  8. Stress And Anxiety: 2 people, 5.71%
  9. Migraine (headache): 2 people, 5.71%
  10. Impaired Gastric Emptying: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and Prochlorperazine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levothroid and Prochlorperazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prochlorperazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levothroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prochlorperazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium and prochlorperazine (the active ingredients of Levothroid and Prochlorperazine, respectively), and Levothroid and Prochlorperazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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