Levothroid and Tekturna drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Tekturna (aliskiren hemifumarate). Common drug interactions include blood creatinine increased among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Levothroid and Tekturna. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Levothroid?
Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.
What is Tekturna?
Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.
13 people who take Levothroid and Tekturna together, and have interactions are studied.

What are the common drug interactions of Levothroid and Tekturna, by gender? *:
female:
- Blood creatinine increased
- Dizziness
- Lip blister
- Lip exfoliation
- Lip swelling
- Pruritus (severe itching of the skin)
- Rash
- Secretion discharge
- Upper respiratory tract infection
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- International normalised ratio increased
- Lung neoplasm (tumour of lung)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Proteinuria (presence of protein in the urine)
- Renal injury (kidney injury)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Type 2 diabetes mellitus
- Acute respiratory failure
What are the common drug interactions of Levothroid and Tekturna, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Cardiac failure congestive
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Type 2 diabetes mellitus
40-49:
n/a
50-59:
- Acute respiratory failure
- Cardiac arrest
- Cardiomyopathy (weakening of the heart muscle)
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
60+:
- Dyspnoea (difficult or laboured respiration)
- Lip blister
- Blood creatine increased
- Blood creatinine increased
- Blood glucose increased
- Blood magnesium decreased
- Blood potassium increased
- Blood sodium decreased
- Blood urea increased
- Bradycardia (abnormally slow heart action)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 38.46%
- Gastric Ulcer (stomach ulcer): 4 people, 30.77%
- Gastric Disorder (disease of stomach): 4 people, 30.77%
- Iron Deficiency: 3 people, 23.08%
- Anaemia (lack of blood): 3 people, 23.08%
- Renal Cell Carcinoma (a kidney cancer): 1 person, 7.69%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.69%
- Pain: 1 person, 7.69%
- Oedema (fluid collection in tissue): 1 person, 7.69%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Levothroid and Tekturna?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Levothroid (8,974 reports)
- Tekturna (4,730 reports)
Browse all drug interactions of Levothroid and Tekturna:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Levothroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tekturna:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levothroid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tekturna and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on levothyroxine sodium and aliskiren hemifumarate (the active ingredients of Levothroid and Tekturna, respectively), and Levothroid and Tekturna (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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