Levoxyl and Dexedrine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levoxyl (levothyroxine sodium) and Dexedrine (dextroamphetamine sulfate). Common drug interactions include somnolence among females and pancreatitis acute among males.

The phase IV clinical study analyzes what interactions people have when they take Levoxyl and Dexedrine. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.

What is Dexedrine?

Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.

On Jul, 13, 2026

60 people who take Levoxyl and Dexedrine together, and have interactions are studied.

Levoxyl and Dexedrine drug interactions.

What are the common drug interactions of Levoxyl and Dexedrine, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Vitamin d deficiency
Cardiac disorder
Pneumonia
Cardiac valve disease (heart valve disease)
Tremor (trembling or shaking movements in one or more parts of your body)
Pain
Alanine aminotransferase increased
Arthropathy
Aspartate aminotransferase increased

male:

Pancreatitis acute (sudden inflammation of pancreas)
Weight decreased
Insulin resistance
Obesity (having too much body fat)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Type 2 diabetes mellitus
Anxiety
Balance disorder
Confusion

What are the common drug interactions of Levoxyl and Dexedrine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Fall
Hunger
Ill-defined disorder
Intervertebral disc protrusion (spinal disc protrusion)
Oral disorder (mouth disease)
Spinal column injury (spinal cord bone injury)
Therapeutic response unexpected
Vitamin d deficiency
Drug effect increased

40-49:

Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Muscle twitching
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

50-59:

Pancreatitis acute (sudden inflammation of pancreas)
Weight decreased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Asthma
Pneumonia
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Seasonal allergy (allergic condition due to certain season)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased

60+:

Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Mucosal inflammation (infection of mucous membrane)
Muscle twitching
Nasal discomfort
Nasal oedema (fluid collection in nose)
Oedema peripheral (superficial swelling)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Rash

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 42 people, 70.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 33 people, 55.00%
High Blood Pressure: 8 people, 13.33%
Depression: 8 people, 13.33%
High Blood Cholesterol: 6 people, 10.00%
Drowsiness: 5 people, 8.33%
Memory Loss: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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