Levoxyl and Fludrocortisone acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levoxyl (levothyroxine sodium) and Fludrocortisone acetate (fludrocortisone acetate). Common drug interactions include infusion site haemorrhage among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Levoxyl and Fludrocortisone acetate. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.

What is Fludrocortisone acetate?

Fludrocortisone acetate has active ingredients of fludrocortisone acetate. It is often used in hypotension. eHealthMe is studying from 2,859 Fludrocortisone acetate users. Check the latest studies of Fludrocortisone acetate.

On Jul, 17, 2026

19 people who take Levoxyl and Fludrocortisone acetate together, and have interactions are studied.

Levoxyl and Fludrocortisone acetate drug interactions.

What are the common drug interactions of Levoxyl and Fludrocortisone Acetate, by gender? *:

female:

Infusion site haemorrhage (bleeding from infusion site)
Infusion site pain
Hypersensitivity
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Stress
Cytomegalovirus infection
Epstein-barr virus infection
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Laryngitis (inflammation of the larynx)
Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)

male:

Asthenia (weakness)
Death
Fall
Hypersensitivity
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pyrexia (fever)
Rash erythematous (redness of the skin)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

What are the common drug interactions of Levoxyl and Fludrocortisone Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bacterial infection
Contusion (a type of hematoma of tissue in which capillaries)
Cytomegalovirus infection
Epstein-barr virus infection
Hypersensitivity
Infectious mononucleosis (infection usually caused by the epstein-barr virus)
Infusion site haemorrhage (bleeding from infusion site)
Infusion site pain
Laryngitis (inflammation of the larynx)
Pneumonia mycoplasmal (mycoplasma pneumonia (mp) is a contagious respiratory infection)

40-49:

Anxiety
Depression
Dyspnoea (difficult or laboured respiration)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Venous thrombosis (blood clot (thrombus) that forms within a vein)

50-59:

Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
Bone marrow failure
Abdominal pain upper
Cough
Decreased appetite
Haemorrhagic disorder (bleeding disorder)
Liver disorder (liver diseases)

60+:

Fall
Asthenia (weakness)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Death
Dizziness
Hypersensitivity
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Injury
Loss of consciousness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 36.84%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 15.79%
Chronic Renal Failure (kidney failure): 3 people, 15.79%
Osteoporosis (bones weak and more likely to break): 2 people, 10.53%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.26%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.26%
Heart Rate Increased: 1 person, 5.26%
Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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