Levoxyl and Nitrofurantoin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levoxyl (levothyroxine sodium) and Nitrofurantoin (nitrofurantoin, macrocrystalline). Common drug interactions include blood triglycerides increased among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Levoxyl and Nitrofurantoin. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Levoxyl?

Levoxyl has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 25,178 Levoxyl users. Check the latest studies of Levoxyl.

What is Nitrofurantoin?

Nitrofurantoin has active ingredients of nitrofurantoin, macrocrystalline. It is often used in urinary tract infection. eHealthMe is studying from 4,837 Nitrofurantoin users. Check the latest studies of Nitrofurantoin.

On Jul, 09, 2026

28 people who take Levoxyl and Nitrofurantoin together, and have interactions are studied.

Levoxyl and Nitrofurantoin drug interactions.

What are the common drug interactions of Levoxyl and Nitrofurantoin, by gender? *:

female:

Blood triglycerides increased
Cardiac disorder
Chills (felling of cold)
Chronotropic incompetence (inability of the heart to increase its rate appropriately in response to increased activity or metabolic need)
Cold sweat
Colitis (inflammation of colon)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dehydration (dryness resulting from the removal of water)
Drug effect decreased

male:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Amylase increased
Depression
Fall
Fatigue (feeling of tiredness)
Food intolerance (inability to have food)
Hypophagia (reduced food intake)
Immune reconstitution syndrome (immune recovery syndrome)
Insomnia (sleeplessness)

What are the common drug interactions of Levoxyl and Nitrofurantoin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bile duct stone
Depression
Duodenal ulcer
Immune reconstitution syndrome (immune recovery syndrome)
Oral fungal infection
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)

50-59:

Incisional hernia (hernia caused by an incompletely-healed surgical wound)
Injection site induration
Post procedural haematoma (post procedural clotting of blood)
Procedural site reaction
Osteoporosis (bones weak and more likely to break)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Incision site haemorrhage (bleeding from incision site)

60+:

Diarrhoea
Haematochezia (passage of stools containing blood)
Fall
Fatigue (feeling of tiredness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Vomiting
Weight decreased
Flushing (the warm, red condition of human skin)
Actinic keratosis (skin disease due to sun exposure)
Arrhythmia (irregular heartbeat)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 17.86%
Osteoporosis (bones weak and more likely to break): 4 people, 14.29%
High Blood Cholesterol: 4 people, 14.29%
Pain: 3 people, 10.71%
Asthma: 3 people, 10.71%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 7.14%
High Blood Pressure: 2 people, 7.14%
Heart Rate Irregular: 2 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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